Neutron capture therapy device and operation method of monitoring system thereof

Abstract

Disclosed are a neutron capture therapy device and an operation method of a monitoring system. The neutron capture therapy device includes a neutron beam irradiation system, a detection system and the monitoring system. The neutron beam irradiation system generates a neutron beam for performing neutron irradiation therapy on a sick body. The detection system is used for detecting irradiation parameters during a neutron beam irradiation therapy, and the monitoring system is used for controlling the whole neutron beam irradiation process. The monitoring system includes a storage part for storing the irradiation parameters, a control part for executing a therapy plan according to the irradiation parameters stored in the storage part, and a correction part for correcting part of the irradiation parameters stored in the storage part. The disclosure improves the accuracy of the dosage of the neutron beam for irradiating the sick body.

What is claimed is: 
     
         1 . A neutron capture therapy device, comprising
 a neutron beam irradiation system configured to generate a neutron beam,   a detection system configured to detect irradiation parameters, and   a monitoring system configured to control the whole neutron beam irradiation process and comprising
 a storage part configured to store the irradiation parameters, 
 a control part configured to perform a therapy plan according to the irradiation parameters stored in the storage part, and 
 a correction part configured to correct a part of the irradiation parameters stored in the storage part. 
   
     
     
         2 . The neutron capture therapy device of  claim 1 , wherein the irritation parameters comprise a remaining irradiation time, and the correction part corrects the remaining irradiation time. 
     
     
         3 . The neutron capture therapy device of  claim 2 , wherein the corrected remaining irradiation time t r  is calculated by using a formula (2-2) and a formula (2-3): 
       
         
           
             
               
                 
                   
                     
                       D 
                       _ 
                     
                     = 
                     
                       
                         D 
                         r 
                       
                       t 
                     
                   
                 
                 
                   
                     ( 
                     
                       2 
                       - 
                       2 
                     
                     ) 
                   
                 
               
             
           
         
         
           
             
               
                 
                   
                     
                       t 
                       r 
                     
                     = 
                     
                       
                         
                           D 
                           total 
                         
                         - 
                         
                           D 
                           r 
                         
                       
                       
                         D 
                         _ 
                       
                     
                   
                 
                 
                   
                     ( 
                     
                       2 
                       - 
                       3 
                     
                     ) 
                   
                 
               
             
           
         
         where t is an implemented irradiation time,  D  is an average neutron dosage value in a period oft, D r  is a real-time neutron dosage detected by the detection system, and D total  is a preset neutron dosage. 
       
     
     
         4 . The neutron capture therapy device of  claim 1 , wherein the irradiation parameters comprise a neutron dosage rate, and the correction part corrects the neutron dosage rate. 
     
     
         5 . The neutron capture therapy device of  claim 4 , wherein the corrected neutron dosage rate I r  is calculated by using a formula (2-5): 
       
         
           
             
               
                 
                   
                     
                       I 
                       r 
                     
                     = 
                     
                       
                         
                           D 
                           total 
                         
                         - 
                         
                           D 
                           r 
                         
                       
                       
                         
                           t 
                           0 
                         
                         - 
                         t 
                       
                     
                   
                 
                 
                   
                     ( 
                     
                       2 
                       - 
                       5 
                     
                     ) 
                   
                 
               
             
           
         
         where t is an implemented irradiation time, to is a preset irradiation time, D r  is a real-time neutron dosage detected by the detection system, and D total  is a preset neutron dosage. 
       
     
     
         6 . The neutron capture therapy device of  claim 3 , wherein the irradiation parameters comprise a boron concentration, and the correction part corrects the boron concentration. 
     
     
         7 . The neutron capture therapy device of  claim 3 , wherein the irradiation parameters comprise preset irradiation parameters, real-time irradiation parameters and corrected irradiation parameters, and the monitoring system further comprises an input part configured to input the preset irradiation parameters, a reading part configured to read the real-time irradiation parameters detected by the detection system, a calculation part configured to calculate the irradiation parameters stored in the storage part, a determination part configured to determine, according to a calculation result of the calculation part, whether the irradiation parameters are needed to be corrected, and a display part configured to display at least the remaining irradiation time of the irradiation parameters in real time. 
     
     
         8 . The neutron capture therapy device of  claim 7 , wherein before the preset irradiation parameters are corrected, the storage part stores the preset irradiation parameters, and the remaining irradiation time displayed by the display part is a difference value between the preset irradiation time and an actually implemented irradiation time; and after the preset irradiation parameters are corrected, the storage part stores latest corrected irradiation parameters, and the remaining irradiation time displayed by the display part is the corrected remaining irradiation time. 
     
     
         9 . The neutron capture therapy device of  claim 8 , wherein in response to a difference value between the real-time irradiation parameter and the preset irradiation parameter calculated by the calculation part being greater than a first threshold, or in response to the real-time irradiation parameter being greater than a second threshold or less than a third threshold, the determination part gives an instruction of correcting the irradiation parameters. 
     
     
         10 . The neutron capture therapy device of  claim 3 , wherein the detection system comprises a neutron dosage detection device configured to detect the real-time neutron dosage in real time, a temperature detection device configured to detect temperature of the neutron beam irradiation system, a displacement detection device configured to detect whether an object to be irradiated generates displacement during therapy, and a boron concentration detection device configured to detect the boron concentration, the is a boron concentration in a body of the object to be irradiated. 
     
     
         11 . The neutron capture therapy device of  claim 10 , wherein the neutron dosage detection device comprises a detector configured to receive the neutron beam and output a signal, a signal processing unit configured to process the signal output from the detector, a counter configured to count a signal output from the signal processing unit to obtain a counting rate, a conversion unit configured to convert the counting rate recorded by the counter into a neutron flux rate or a neutron dosage rate, an integration unit configured to integrate the neutron flux rate or the neutron dosage rate to obtain the neutron dosage, and a display configured to display the neutron dosage. 
     
     
         12 . An operation method of the monitoring system of the neutron capture therapy device of  claim 7 , comprising:
 S1: inputting, by the input part, the preset irradiation parameters;   S2: storing, by the storage part, the irradiation parameters;   S3: performing, by the control part, the therapy plan according to the irradiation parameters stored in the storage part;   S4: reading, by the reading part, the real-time irradiation parameters detected by the detection system;   S5: calculating, by the calculation part, the irradiation parameters stored in the storage part and the real-time irradiation parameters read by the reading part;   S6: determining, by the determination part, whether the irradiation parameters stored in the storage part are needed to be corrected, according to the calculation result of the calculation part;   S7: correcting, by the correction part, a latest set of irradiation parameters in the storage part, in response to the determination part determining to correct the irradiation parameters stored in the storage part;   not performing, by the correction part, a correction action, in response to the determination part determining not to correct the latest set of irradiation parameters; and   S8: displaying, by the display part, the remaining irradiation time in real time according to the latest set of irradiation parameters stored in the storage part.   
     
     
         13 . The operation method of the monitoring system of the neutron capture therapy device of  claim 12 , wherein before the preset irradiation parameters are corrected, the storage part stores the preset irradiation parameters, and the display part displays the remaining irradiation time and other preset irradiation parameters in real time; and after the preset irradiation parameters are corrected, the storage part stores a latest set of corrected irradiation parameters, and the display part displays the corrected remaining irradiation time and the latest set of other corrected irradiation parameters in real time. 
     
     
         14 . An operation method of the monitoring system of the neutron capture therapy device of  claim 10 , comprising:
 S1: inputting, by the input part, the preset irradiation parameters;   S2: storing, by the storage part, the irradiation parameters;   S3: performing, by the control part, the therapy plan according to the irradiation parameters stored in the storage part;   S4: reading, by the reading part, the real-time irradiation parameters detected by the detection system;   S5: calculating, by the calculation part, the irradiation parameters stored in the storage part and the real-time irradiation parameters read by the reading part;   S6: determining, by the determination part, whether the irradiation parameters stored in the storage part are needed to be corrected, according to the calculation result of the calculation part;   S7: correcting, by the correction part, a latest set of irradiation parameters in the storage part, in response to the determination part determining to correct the irradiation parameters stored in the storage part;   not performing, by the correction part, a correction action, in response to the determination part determining not to correct the latest set of irradiation parameters; and   S8: displaying, by the display part, the remaining irradiation time in real time according to the latest set of irradiation parameters stored in the storage part.   
     
     
         15 . The operation method of the monitoring system of the neutron capture therapy device of  claim 14 , wherein before the preset irradiation parameters are corrected, the storage part stores the preset irradiation parameters, and the display part displays the remaining irradiation time and other preset irradiation parameters in real time; and after the preset irradiation parameters are corrected, the storage part stores a latest set of corrected irradiation parameters, and the display part displays the corrected remaining irradiation time and the latest set of other corrected irradiation parameters in real time.