Marine extract compositions and methods of use

Abstract

Compositions comprising extracts from marine organisms show beneficial effects on skin ailments. Fine lines, wrinkles, and sagging in skin are improved with the application of compositions with marine extracts. Production of collagen, elastin and hyaluronic acid are increased after application of the compositions.

What is claimed is: 
     
         1 . A topical composition comprising a first tissue extract from abalone, alga, bivalve, crustacean, or cyanobacteria and a second tissue extract from sea cucumber, wherein, wherein the topical composition is suitable for dermatologic application, wherein the topical composition is a gel, cream, plasma, lotion, foam, facial mask, or skin mask, and wherein the second tissue extract is produced by a process of extraction by a polar solvent. 
     
     
         2 . The composition of  claim 1  wherein the composition is useful for treating rosacea when applied to skin and wherein daily application of the composition to affected skin of a subject with rosacea for 30 days results in a significant improvement or disappearance of rosacea. 
     
     
         3 . The composition of  claim 1  wherein when applied daily to skin of a subject with rosacea for 30 days results in a significant improvement or disappearance of rosacea. 
     
     
         4 . The composition of  claim 1  wherein the polar solvent is selected from the group consisting of dimethyl sulfoxide (DMSO), isopropyl alcohol, ethanol, methanol, and acetic acid.. 
     
     
         5 . The composition of  claim 4  wherein the polar solvent is DMSO. 
     
     
         6 . The composition of  claim 1  wherein the first tissue extract is an abalone tissue extract. 
     
     
         7 . The composition of  claim 6  wherein the abalone tissue extract is a polar solvent extract, a non-polar solvent extract, or a combination thereof. 
     
     
         8 . The composition of  claim 1  wherein the sea cucumber is selected from the group consisting of  Holothuria   mexicana ,  Holothuria   californicus ,  Holothuria   scabra ,  Sticha   pus   chlorontus ,  Sticha   pus   horrens ,  Stichopus   japonicus ,  Apostichopus   japonicus , and  Cucumaria   japonica . 
     
     
         9 . The composition of  claim 1  wherein the second tissue extract is extracted from at least one sea cucumber part selected from the group consisting of body walls, muscles, visceras, and gonads. 
     
     
         10 . A topical composition comprising a first tissue extract from abalone and a second tissue extract from a sea cucumber, wherein the sea cucumber tissue extract is produced by a process of extraction by a polar solvent wherein the topical composition is suitable for dermatologic application, wherein the topical composition is a gel, cream, plasma, lotion, foam, facial mask, or skin mask, and wherein application of the composition to the skin of a subject causes an increase in production of collagen, elastin, hyaluronic acid, fibrocytes, and new blood vessels, and wherein the polar solvent is dimethyl sulfoxide. 
     
     
         11 . A method of treatment of a subject in need thereof comprising the step of administering a composition of  claim 1 . 
     
     
         12 . The method of  claim 11  wherein the administration step is a step of topical administration. 
     
     
         13 . The method of  claim 12  wherein the subject in need thereof has a skin ailment selected from the group consisting of the skin ailment is selected from the group consisting of fine lines, wrinkles, sagging, large pores, lentigines, keratoses, rosacea, dry skin, irritated skin and sensitive skin. 
     
     
         14 . The method of  claim 13  wherein the skin ailment is due to a cause selected from the group consisting of sun light, ultraviolet light, wind, heat, humidity, soaps, age and health.