Conduit vascular implant sealing device for reducing endoleaks

Abstract

A sealing device for use as a vascular implant including a frame, the frame having an inflow edge and an outflow edge relative to axial blood flow within a vessel, wherein at least a partial axial extent of the frame is configured to decrease in axial length when expanded from a radially compressed configuration to a radially expanded configuration. The sealing device also includes a membrane layer coupled to a radially outward surface of the at least partial axial extent of the frame between the inflow edge and the outflow edge of the frame, wherein the membrane layer is coupled to the frame at one or more axially spaced connection points such that at least a portion of the membrane layer projects radially outward relative to the frame when the frame is in the radially-expanded configuration.

1 . A sealing device for use as a vascular implant comprising:
 a frame, the frame having an inflow edge and an outflow edge relative to axial blood flow within a vessel, wherein an at least partial axial extent of the frame is configured to decrease in axial length when expanded from a radially compressed configuration to a radially expanded configuration; and   a membrane layer coupled to the at least partial axial extent of the frame between the inflow edge and the outflow edge of the frame, wherein the membrane layer is coupled to an outer surface of the at least partial axial extent of the frame at one or more axially spaced connection points such that at least a portion of the membrane layer projects radially outward relative to the frame when the at least partial axial extent of the frame is in the radially-expanded configuration, the portion of the membrane layer being included between the one or more axially spaced connection points such that the transverse curvilinear extent does not have underlying frame members.   
     
     
         2 . The sealing device of  claim 1 , wherein the at least partial axial extent of the frame is formed as a lattice structure. 
     
     
         3 . The sealing device of  claim 2 , wherein the membrane layer is coupled to the lattice structure at a plurality of axially-spaced and circumferentially-distributed connection points. 
     
     
         4 . The sealing device of  claim 3 , wherein the membrane layer is coupled to the lattice structure by a plurality of sutures. 
     
     
         5 . The sealing device of  claim 1 , wherein the one or more axially spaced connection points of the frame include a plurality of circumferentially-distributed connection points proximate to the inflow edge of the at least partial axial extent of the frame. 
     
     
         6 . The sealing device of  claim 1 , wherein the one or more axially spaced connection points of the frame include a plurality of circumferentially-distributed connection points proximate to the outflow edge of the at least partial axial extent of the frame. 
     
     
         7 . The sealing device of  claim 1 , wherein the axially spaced connection points of the frame include one or more circumferentially-distributed connection points proximate to the outflow edge of the at least partial axial extent of the frame, one or more circumferentially-distributed connection points proximate to the inflow edge of the at least partial axial extent of the frame, and one or more intermediate connection points located axially between the connection points proximate the outflow edge and the connections points proximate the inflow edge. 
     
     
         8 . The sealing device of  claim 7 , wherein the one or more intermediate connection points enforce an inflow-angled fold in the membrane layer. 
     
     
         9 . The sealing device of  claim 7 , wherein the one or more intermediate connection points enforce an outflow-angled fold in the membrane layer. 
     
     
         10 . The sealing device of  claim 7 , wherein the one or more intermediate connection points enforces both an inflow-angled and an outflow-angled fold in the membrane layer. 
     
     
         11 . The sealing device of  claim 1 , wherein the membrane layer is formed of at least one of processed mammalian pericardium tissue, a biocompatible fabric, or a polymer material. 
     
     
         12 . The sealing device of  claim 11 , wherein the membrane layer is formed of at least one of porcine or bovine pericardium tissue. 
     
     
         13 . The sealing device of  claim 11 , wherein the membrane layer is formed of a substantially dry tissue. 
     
     
         14 . The sealing device of  claim 13 , wherein the sealing device is in a radially-compressed condition, associated to a delivery system, and provided together with the delivery system in a sterile condition within an internally sterile package. 
     
     
         15 . The sealing device of  claim 1 , wherein a circumferential extent of the membrane layer exceeds a circumferential extent of the frame. 
     
     
         16 . The sealing device of  claim 1 , wherein a circumferential extent of the membrane layer does not exceed a circumferential extent of the frame. 
     
     
         17 . The sealing device of  claim 1 , wherein the membrane layer extends over an entire axial length of the frame. 
     
     
         18 . The sealing device of  claim 1 , wherein the membrane layer extends over only a portion of an axial length of the frame. 
     
     
         19 . The sealing device of  claim 1 , wherein the membrane layer axially extends beyond at least one of the inflow edge or the outflow edge of the frame. 
     
     
         20 . The sealing device of  claim 1 , wherein the radially projecting portion of the membrane layer is configured to contact an inner wall of the vessel to cause an impeding of blood flow over an outer surface of the sealing device. 
     
     
         21 .- 44 . (canceled)