Methods and apparatus for removing material from within a mammalian cavity using an insertable endoscopic instrument

Abstract

An endoscope for removing tissue at a surgical site includes an elongated tubular body insertable within a mammalian cavity of a patient. An instrument channel extends between a first opening at a distal end and a second opening at a proximal end of the tubular body and is sized and configured to receive a surgical cutting assembly that includes an aspiration channel configured to remove material entering the endoscope via a distal end of the surgical cutting assembly. A torque generation component configured to generate torque is positioned within the distal end and configured to provide the generated torque to a coupling component. The coupling component is positioned at the distal end of the elongated tubular member and configured to actuate a cutting component of the surgical cutting assembly responsive to actuation of the torque generation component.

What is claimed is: 
     
         1 . A method of removing material from within a mammalian cavity of a patient, comprising:
 inserting a flexible endoscope within an opening to a mammalian cavity of a patient, the flexible endoscope inserted within the opening via a distal end of the endoscope;   disposing a surgical cutting assembly within an instrument channel of the flexible endoscope, the surgical cutting assembly inserted into the instrument channel via an instrument channel opening to the instrument channel at a proximal end of the endoscope that remains outside the opening to the mammalian cavity, the surgical cutting assembly including a cutter assembly having an outer cannula, an inner cannula disposed within an outer cannula, and a cutting window defined along a portion of a radial wall of the outer cannula, a proximal end of the inner cannula fluidly coupled to an aspiration channel that extends along a length of the flexible endoscope, the inner cannula configured to rotate relative to the outer cannula to cut material entering the cutting window of the outer cannula;   positioning, by rotating the outer cannula of the surgical cutting assembly, the cutting window at the material within the mammalian cavity to be resected;   providing torque to rotate the inner cannula relative to the outer cannula, the torque provided to the inner cannula via a flexible torque component extending from a proximal end of the endoscope to the distal end of the endoscope, the torque sufficient to rotate the inner cannula relative to the outer cannula to resect at least a portion of the material entering the cutting window of the outer cannula; and   actuating a sample retrieval component of the surgical cutting assembly to remove the resected material via the aspiration channel.   
     
     
         2 . A method of removing lesions from within a mammalian cavity of a patient, comprising:
 inserting a flexible endoscope within an opening to a mammalian cavity of a patient;   disposing an endoscopic instrument within an instrument channel of the flexible endoscope to remove at least one lesion from within the mammalian cavity, the endoscopic instrument including a cutting assembly having an outer cannula, an inner cannula disposed within an outer cannula, and an opening defined along a portion of a radial wall of the outer cannula, the inner cannula rotatably coupled to a flexible torque component having a length that extends along a length of the flexible endoscope, the flexible torque component, upon actuation, providing torque to the inner cannula;   providing irrigation fluid from a lavage port of the endoscopic instrument that remains outside the flexible endoscope while the endoscopic instrument is disposed within the instrument channel, the lavage port fluidly coupled to the outer cannula through a rotational coupler coupling the lavage port to an outer tubing connected to the outer cannula, the rotational coupler allowing the outer tubing and the outer cannula to rotate relative to the lavage port upon rotating a portion of the rotational coupler;   rotating, via rotation of the portion of the rotational coupler, the outer cannula to a position in which the opening of the outer cannula is viewable via a camera of the flexible endoscope;   positioning the opening at the lesion of the mammalian cavity;   actuating the flexible torque component to rotate the inner cannula relative to the outer cannula, the inner cannula cutting a portion of the lesion as the inner cannula rotates adjacent to the opening; and   actuating a sample retrieval component of the endoscopic instrument to remove the cut portions of the lesion from within the mammalian cavity via an aspiration channel defined by an inner wall of the inner cannula and the flexible torque component.   
     
     
         3 . The method of  claim 2 , wherein disposing the endoscopic instrument within the instrument channel of the flexible endoscope includes inserting a distal end of the endoscopic instrument in the instrument channel of the flexible endoscope. 
     
     
         4 . The method of  claim 2 , further comprising engaging a proximal connector that is coupled to the flexible torque component and positioned at a proximal end of the endoscopic instrument with a drive assembly configured to provide torque to the flexible torque component. 
     
     
         5 . The method of  claim 2 , further comprising fluidly coupling a vacuum source to a distal end of the endoscopic instrument to remove, from the endoscopic instrument, portions of the lesion entering the endoscopic instrument via the opening of the outer cannula. 
     
     
         6 . The method of  claim 2 , wherein the flexible torque component includes a flexible torque coil having a plurality of layers of one or more threads, each of the plurality of layers is wound in a direction opposite to a direction in which one or more adjacent layers of the plurality of layers is wound and the aspiration channel is partially defined by an inner wall of the flexible torque coil. 
     
     
         7 . The method of  claim 2 , wherein actuating the flexible torque component and actuating a sample retrieval component of the endoscopic instrument includes actuating the flexible torque component and actuating the sample retrieval component of the endoscopic instrument simultaneously. 
     
     
         8 . The method of  claim 2 , wherein actuating the flexible torque component includes providing torque to the inner cannula that is sufficient to cut at least a portion of the lesion. 
     
     
         9 . The method of  claim 2 , wherein actuating the flexible torque component includes actuating the flexible torque component to cause an inner cannula of the cutting assembly to rotate relative to the outer cannula via a foot pedal. 
     
     
         10 . The method of  claim 2 , wherein the lesion is a first lesion and further comprising:
 upon cutting at least a portion of the first lesion and without removing the endoscopic instrument from the flexible endoscope, positioning the opening of the outer cannula at a second lesion within the mammalian cavity;   actuating the flexible torque component to rotate the inner cannula relative to the outer cannula, the inner cannula cutting at least a portion of the second lesion; and   actuating the sample retrieval component of the endoscopic instrument to remove the cut portion of the second lesion from within the mammalian cavity.   
     
     
         11 . A method of removing lesions from within a patient, comprising:
 inserting a flexible endoscope within an opening of a patient;   disposing an endoscopic instrument within an instrument channel of the flexible endoscope to remove a lesion from the surgical site, the endoscopic instrument including a cutting assembly having an outer cannula, an inner cannula disposed within an outer cannula, and an opening defined along a portion of a radial wall of the outer cannula, the inner cannula rotatably coupled to a flexible torque component having a length that extends along a length of the flexible endoscope, the flexible torque component, upon actuation, providing torque to the inner cannula;   positioning the opening of the outer cannula at the lesion;   actuating the flexible torque component to rotate the inner cannula relative to the outer cannula, the inner cannula cutting a portion of the lesion as the inner cannula rotates adjacent to the opening; and   actuating a sample retrieval component of the endoscopic instrument to remove the cut portions of the lesion from within the patient via an aspiration channel defined by an inner wall of the inner cannula and the flexible torque component.   
     
     
         12 . The method of  claim 11 , further comprising providing irrigation fluid from a lavage port of the endoscopic instrument that remains outside the flexible endoscope while the endoscopic instrument is disposed within the instrument channel, the lavage port fluidly coupled to the outer cannula through a rotational coupler coupling the lavage port to an outer tubing connected to the outer cannula, the rotational coupler allowing the outer tubing and the outer cannula to rotate relative to the lavage port upon rotating a portion of the rotational coupler. 
     
     
         13 . The method of  claim 12 , further comprising rotating, via rotation of the portion of the rotational coupler, the outer cannula to a position in which the opening of the outer cannula is viewable via a camera of the flexible endoscope. 
     
     
         14 . The method of  claim 11 , wherein disposing the endoscopic instrument within the instrument channel of the flexible endoscope includes inserting a distal end of the endoscopic instrument in the instrument channel of the flexible endoscope. 
     
     
         15 . The method of  claim 11 , further comprising engaging a proximal connector that is coupled to the flexible torque component and positioned at a proximal end of the endoscopic instrument with a drive assembly configured to provide torque to the flexible torque component. 
     
     
         16 . The method of  claim 11 , further comprising fluidly coupling a vacuum source to a distal end of the endoscopic instrument to remove, from the endoscopic instrument, cut portions of the lesion entering the endoscopic instrument via the opening of the outer cannula. 
     
     
         17 . The method of  claim 11 , wherein the flexible torque component includes a flexible torque coil having a plurality of layers of one or more threads, each of the plurality of layers is wound in a direction opposite to a direction in which one or more adjacent layers of the plurality of layers is wound and the aspiration channel is partially defined by an inner wall of the flexible torque coil. 
     
     
         18 . The method of  claim 11 , wherein actuating the flexible torque component and actuating a sample retrieval component of the endoscopic instrument includes actuating the flexible torque component and actuating the sample retrieval component of the endoscopic instrument simultaneously. 
     
     
         19 . The method of  claim 11 , wherein actuating the flexible torque component includes providing torque to the inner cannula that is sufficient to cut at least a portion of the lesion. 
     
     
         20 . The method of  claim 11 , wherein the lesion is a first lesion and further comprising:
 upon cutting at least a portion of the first lesion and without removing the endoscopic instrument from the flexible endoscope, positioning the opening of the outer cannula at a second lesion at another surgical site;   actuating the flexible torque component to rotate the inner cannula relative to the outer cannula, the inner cannula cutting at least a portion of the second lesion; and   actuating the sample retrieval component of the endoscopic instrument to remove the cut portion of the second lesion from within the patient.