Fungicidal combinations

Abstract

The present disclosure relates to fungicidal combinations, compositions including the fungicidal combinations, and to a method of controlling fungal diseases using the combinations. The combination includes at least one demethylation inhibitor; at least one succinate dehydrogenase (SDH) inhibitor; at least one RNA polymerase I inhibitor; and at least one ß-tubulin assembly inhibitor and/or at least one multi-site fungicide.

1 . A fungicidal combination, comprising:
 at least one demethylation inhibitor;   at least one succinate dehydrogenase (SDH) inhibitor;   at least one RNA polymerase I inhibitor; and   at least one ß-tubulin assembly inhibitor and/or at least one multi-site fungicide.   
     
     
         2 . The fungicidal combination as claimed in  claim 1 , wherein the demethylation inhibitor fungicide comprises azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, or a combination thereof. 
     
     
         3 . The fungicidal combination as claimed in  claim 1 , wherein the demethylation inhibitor is ipconazole. 
     
     
         4 . The fungicidal combination as claimed in  claim 1 , wherein the SDH inhibitor comprises benodanil, boscalid, carboxin, fenfuram, flutolanil, furametpyr, mepronil, oxycarboxin, penthiopyrad, thifluzamide, or a combination thereof. 
     
     
         5 . The fungicidal combination as claimed in  claim 1 , wherein the SDH inhibitor is carboxin. 
     
     
         6 . The fungicidal combination as claimed in  claim 1 , wherein the RNA polymerase I inhibitor comprises benalaxyl, furalaxyl, metalaxyl, metalaxyl-m, oxadixyl, ofurace, or a combination thereof. 
     
     
         7 . The fungicidal combination as claimed in  claim 1 , wherein the RNA polymerase I inhibitor is metalaxyl or metalaxyl-m. 
     
     
         8 . The fungicidal combination as claimed in  claim 1 , wherein the ß-tubulin assembly inhibitor comprises benomyl, carbendazim, fuberidazole, thiabendazole, thiophanate, thiophanate-methyl, or a combination thereof. 
     
     
         9 . The fungicidal combination as claimed in  claim 1 , wherein the ß-tubulin assembly inhibitor is thiophanate or thiophanate-methyl. 
     
     
         10 . The fungicidal combination as claimed in  claim 1 , wherein the multisite inhibitor comprises ferbam, mancozeb, maneb, metiram, propineb, thiram, zineb, ziram, captan, captafol, folpet, chlorothalonil, dichlofluanid, tolylfluanid, dodine, guazatine, iminoctadine, anilazine, dithianon, or a combination thereof. 
     
     
         11 . The fungicidal combination as claimed in  claim 1 , wherein the multisite inhibitor is thiram. 
     
     
         12 . A method of treating seeds, the method comprising applying to the seeds the combination of  claim 1 , wherein the SDHI inhibitor fungicide is applied in an amount in the range from 10 to 50 g ai/100 kg of seeds. 
     
     
         13 . A method of treating seeds, the method comprising applying to the seeds the combination of  claim 1 , wherein the demethylation inhibitor fungicide is applied in an amount in the range from 1 to 5 g ai/100 kg. 
     
     
         14 . A method of treating seeds, the method comprising applying to the seeds the combination of  claim 1 , wherein the RNA polymerase I inhibitor fungicide is applied in an amount in the range from 1 to 5 g ai/100 kg of seeds. 
     
     
         15 . A method of treating seeds, the method comprising applying to the seeds the combination of  claim 1 , wherein the ß-tubulin assembly inhibitor fungicide is applied in an amount in the range from 10 to 60 g ai/100 kg of seeds. 
     
     
         16 . A method of treating seeds, the method comprising applying to the seeds the combination of  claim 1 , wherein the multi-site fungicide is applied in an amount in the range from 200 to 300 g ai/kg. 
     
     
         17 . A method of controlling fungi comprising applying to the locus of a fungus the combination of  claim 1 . 
     
     
         18 . The method of  claim 17 , comprising applying:
 the at least one demethylation inhibitor in an amount ranging from 1 to 5 g ai/100 kg of seeds;   the at least one ß-tubulin assembly inhibitor in an amount ranging from 10 to 60 g ai/100 kg of seeds;   the at least one SDH inhibitor in an amount ranging from 10 to 50 g ai/100 kg of seeds; and   the at least one RNA polymerase I inhibitor in an amount ranging from 1 to 5 g ai/100 kg of seeds.   
     
     
         19 . A kit of parts comprising the fungicidal combination of  claim 1 .