Methods and systems for assessing photoreceptor function

Abstract

A method for non-invasive assessment of photoreceptor function in a mammalian subject comprises exposing a subject's eye to a visible light stimulus to initiate an intrinsic reflectance response in one or a population of photoreceptors and capturing multiple images of photoreceptor's intrinsic reflectance response to the stimulus. Patterns of variability in the intrinsic reflectance response of a single photoreceptor or population of photoreceptors are useful in diagnosis and treatment monitoring of an ocular condition, disease, disorder or a response to treatment for said ocular condition, disease or disorder.

1 . A method for non-invasive assessment of photoreceptor function in a mammalian subject comprising:
 exposing a subject's eye to a visible light stimulus, wherein absorption of visible light by a photoreceptor's photopigment initiates an intrinsic reflectance response from the photoreceptor;   capturing multiple images of the photoreceptor's intrinsic reflectance response to the stimulus over a time period; and   identifying a pattern of variations in the intrinsic reflectance response indicative of an ocular condition, disease, disorder or a response to treatment for said ocular condition, disease or disorder.