Neutron capture therapy apparatus and operation method of monitoring system thereof

Abstract

A neutron capture therapy apparatus includes a neutron beam irradiation system, a detection system and a monitoring system. The neutron beam irradiation system is configured for generating a neutron beam. The detection system is configured for detecting real-time irradiation parameters during a neutron beam irradiation therapy process. The monitoring system is configured for controlling the whole neutron beam irradiation process and includes an input part for inputting preset irradiation parameters, a determination part for determining whether the irradiation parameters need to be corrected and a correction part for correcting some of the irradiation parameters when the determination part determines that the irradiation parameters need to be corrected. When the ratio of the real-time neutron dose detected by the detection system to a preset neutron dose is greater than or equal to a preset value, the determination part of the monitoring system determines that the irradiation parameters need to be corrected.

What is claimed is: 
     
         1 . A neutron capture therapy apparatus, comprising 
 a neutron beam irradiation system configured to generate a neutron beam,   a detection system configured to detect real-time irradiation parameters during a neutron beam irradiation therapy, and   a monitoring system configured to control the whole neutron beam irradiation process and comprising
 an input part configured to input preset irradiation parameters, 
 a determination part configured to determine whether irradiation parameters to be corrected, and 
 a correction part configured to correct a part of the irradiation parameters, in response to the determination part determining that the irradiation parameters are needed to be corrected, and the determination part of the monitoring system determining that the irradiation parameters are needed to be corrected, in response to a ratio of a real-time neutron dosage detected by the detection system to a preset neutron dosage being greater than or equal to a preset value. 
   
     
     
         2 . The neutron capture therapy apparatus of  claim 1 , wherein the correction part adjusts a neutron dosage rate to be a first neutron dosage rate less than a preset neutron dosage rate, in response to the ratio of the real-time neutron dosage to the preset neutron dosage being greater than or equal to the preset value. 
     
     
         3 . The neutron capture therapy apparatus of  claim 2 , wherein the correction part adjusts the neutron dosage rate to be the first neutron dosage rate less than the preset neutron dosage rate, in response to the ratio of the real-time neutron dosage to the preset neutron dosage being greater than or equal to 97%. 
     
     
         4 . The neutron capture therapy apparatus of  claim 3 , wherein the first neutron dosage rate is comprised between ⅕ and ½ of the preset neutron dosage rate. 
     
     
         5 . The neutron capture therapy apparatus of  claim 1 , wherein the monitoring system further comprises a storage part configured to store irradiation parameters, a control part configured to perform a therapy plan according to the irradiation parameters stored in the storage part, and a reading part configured to read the real-time irradiation parameters detected by the detection system. 
     
     
         6 . The neutron capture therapy apparatus of  claim 5 , wherein the monitoring system further comprises a calculation part configured to calculate the irradiation parameters stored in the storage part, and the determination part determines, according to a calculation result of the calculation part, whether the irradiation parameters to be corrected. 
     
     
         7 . The neutron capture therapy apparatus of  claim 6 , wherein the determination part gives an instruction of correcting the irradiation parameters, in response to a difference between the preset irradiation parameter and the real-time irradiation parameter calculated by the calculation part being greater than a first threshold, or the real-time irradiation parameter being greater than a second threshold or less than a third threshold. 
     
     
         8 . The neutron capture therapy apparatus of  claim 4 , wherein the correction part corrects a remaining irradiation time, in response to adjusting, by the correction part, the neutron dosage rate to be ⅕ of the preset neutron dosage rate, and a corrected remaining irradiation time tr is calculated by using a formula (2-4):
           t   r     =         D     t   o   t   a   l       −     D   r               I   d       5               
 where D total  is the preset neutron dosage, D r  is the real-time neutron dosage detected by the detection system, and I d  is the preset neutron dosage rate. 
 
     
     
         9 . The neutron capture therapy apparatus of  claim 8 , wherein a corrected remaining irradiation time tr is calculated by using a formula (2-2) and a formula (2-3), in response to the ratio of the real-time neutron dosage to the preset neutron dosage being less than or equal to 97%: 
       
         
           
             
               
                 D 
                 ¯ 
               
               = 
               
                 
                   
                     D 
                     r 
                   
                 
                 t 
               
             
           
         
       
       
         
           
             
               
                 t 
                 r 
               
               = 
               
                 
                   
                     D 
                     
                       t 
                       o 
                       t 
                       a 
                       l 
                     
                   
                   − 
                   
                     D 
                     r 
                   
                 
                 
                   D 
                   ¯ 
                 
               
             
           
         
       
       . 
     
     
         10 . The neutron capture therapy apparatus of  claim 1 , wherein the monitoring system further comprises a display part configured to display irradiation parameters in real time. 
     
     
         11 . The neutron capture therapy apparatus of  claim 3 , wherein the monitoring system further comprises a display part configured to display irradiation parameters in real time. 
     
     
         12 . An operation method of the monitoring system of the neutron capture therapy apparatus of  claim 1 , comprising:
 inputting, by the input part, the preset irradiation parameters;   determining, by the determination part, whether irradiation parameters to be corrected; and   correcting, by the correction part, the irradiation parameters, in response to the determination part determining that the irradiation parameters are needed to be corrected.   
     
     
         13 . The operation method of the monitoring system of  claim 12 , wherein the monitoring system further comprises a storage part configured to store irradiation parameters, a calculation part configured to calculate the irradiation parameters stored in the storage part, and a reading part configured to read the real-time irradiation parameters detected by the detection system, and the operation method of the monitoring system further comprise calculating, by the calculation part, the irradiation parameters stored in the storage part and the real-time irradiation parameters read by the reading part, and the determination part determines, according to a calculation result of the calculation part, whether the irradiation parameters to be corrected. 
     
     
         14 . The operation method of the monitoring system of  claim 12 , wherein the monitoring system further comprises a display part, and the operation method of the monitoring system further comprise displaying, by the display part, irradiation parameters in real time. 
     
     
         15 . The operation method of the monitoring system of  claim 14 , wherein the storage part stores the preset irradiation parameters, and the display part displays a remaining irradiation time and other preset irradiation parameters in real time, before the preset irradiation parameters are corrected; and the storage part stores a latest set of corrected irradiation parameters, and the display part displays a corrected remaining irradiation time and a latest set of other corrected irradiation parameters in real time, after the preset irradiation parameters are corrected. 
     
     
         16 . The operation method of the monitoring system of  claim 12 , wherein the correction part adjusts a neutron dosage rate to be a first neutron dosage rate less than a preset neutron dosage rate, in response to the ratio of the real-time neutron dosage to the preset neutron dosage being greater than or equal to the preset value. 
     
     
         17 . The operation method of the monitoring system of  claim 16 , wherein the correction part adjusts the neutron dosage rate to be the first neutron dosage rate less than the preset neutron dosage rate, in response to the ratio of the real-time neutron dosage to the preset neutron dosage being greater than or equal to 97%. 
     
     
         18 . The operation method of the monitoring system of  claim 17 , wherein the first neutron dosage rate is comprised between ⅕ and ½ of the preset neutron dosage rate. 
     
     
         19 . The operation method of the monitoring system of  claim 18 , wherein the correction part corrects a remaining irradiation time, in response to adjusting, by the correction part, the neutron dosage rate to be ⅕ of the preset neutron dosage rate, and a corrected remaining irradiation time tr is calculated by using a formula (2-4):
           t   r     =         D     t   o   t   a   l       −     D   r               I   d       5               
 where D total  is the preset neutron dosage, D r  is the real-time neutron dosage detected by the detection system, and I d  is the preset neutron dosage rate. 
 
     
     
         20 . The operation method of the monitoring system of  claim 12 , wherein the monitoring system further comprises a storage part configured to store irradiation parameters, a control part configured to perform a therapy plan according to the irradiation parameters stored in the storage part, and a reading part configured to read the real-time irradiation parameters detected by the detection system.