US2023255857A1PendingUtilityA1
Dental composition containing ion sustained-release glass
Est. expiryMay 30, 2034(~7.9 yrs left)· nominal 20-yr term from priority
Inventors:Daisuke HaraYuji SadakaneKatsura IshikawaHidefumi FujimuraShuji SakamotoAkihiro NagafujiToshiyuki Nakatsuka
A61K 6/70A61K 8/25A61K 8/26A61K 8/19A61K 8/21A61Q 11/00A61K 8/8152A61K 6/20A61K 6/77A61K 2800/56A61K 2800/81A61K 2800/882A61K 2800/95
73
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Claims
Abstract
To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO 2 ; 15% to 30% by mass Al 2 O 3 ; 5% to 20% by mass B 2 O 3 ; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na 2 O.
Claims
exact text as granted — not AI-modified1 - 22 . (canceled)
23 . A dental varnish composition comprising:
an ion sustained-release glass (a); a film component (f); and an organic solvent (g), wherein the film component (f) is made of rosin or a high molecular weight organic compound having a molecular weight of 1000 to 20000, and the organic solvent (g) is any of methanol, ethanol, n-propanol, isopropyl alcohol, acetone, methyl ethyl ketone, and methyl methacrylate.
24 . The dental varnish composition according to claim 23 ,
wherein the ion sustained-release glass (a) is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO 2 ; 15% to 30% by mass Al 2 O 3 ; 5% to 20% by mass B 2 O 3 ; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na 2 O.
25 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition has a 50% particle diameter in a range of 0.01 μm to 100 μm.
26 . The dental varnish composition according to claim 23 ,
wherein the ion sustained-release glass (a) is surface-coated with a silane compound (c) and then surface-treated with an acid polymer (d).
27 . The dental varnish composition according to claim 23 ,
wherein the ion concentration (F1) or the element concentration (F1) attributable to the ion species sustain-released in the distilled water when stirred for 1 hour and the ion concentration (F2) or the element concentration (F2) attributable to the ion species sustained-released in the distilled water when stirred for 2 hours satisfy the relationship of the following Expression (1):
F2>F1 Expression (1).
28 . The dental varnish composition according to claim 23 ,
wherein the pH change after stirring for 5 minutes a mixture of 10 g of a lactic acid water solution with pH adjusted to 4.0 and 0.1 g of the ion sustained-release glass (a) is greater than or equal to 5.5.
29 . The dental varnish composition according to claim 23 ,
wherein the content of the ion sustained-release glass (a) is in the range of 5% to 60% by weight, with respect to the total amount of the dental varnish composition.
30 . The dental varnish composition according to claim 23 ,
wherein the content of the film component (f) is in the range of 20% to 80% by mass.
31 . The dental varnish composition according to claim 23 ,
wherein the content of the organic solvent (g) is in the range of 5% to 30% by mass.
32 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises a fluoride salt.
33 . The dental varnish composition according to claim 32 ,
wherein the fluoride salt is one or more selected from the group consisting of lithium fluoride, sodium fluoride, potassium fluoride, rubidium fluoride, cesium fluoride, beryllium fluoride, magnesium fluoride, calcium fluoride, strontium fluoride, barium fluoride, aluminum fluoride, manganese(II) fluoride, iron(II) fluoride, iron(III) fluoride, silver(I) fluoride, diammine silver fluoride, sodium hydrogenfluoride, potassium hydrogenfluoride, sodium fluorophosphates, potassium hexafluorotitanate, sodium hexafluorosilicate, sodium hexafluorophosphate, pentafluoro-2-sodium stannate(II), and potassium hexafluorozirconate.
34 . The dental varnish composition according to claim 32 ,
wherein the content of the fluoride salt is in the range of 1% to 10% by mass.
35 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises water or one or more hydrophilic compound selected from the group consisting of glycerin, polyethyleneglycol, polypropyleneglycol, 2-hydroxyethylmethacrylate, and polyethyleneglycol dimethacrylate.
36 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises one or more hydrophilic compound selected from the group consisting of glycerin, polyethyleneglycol, polypropyleneglycol, 2-hydroxyethylmethacrylate, and polyethyleneglycol dimethacrylate.
37 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises a coloring agent.
38 . The dental varnish composition according to claim 37 ,
wherein the coloring agent is an organic coloring agent.
39 . The dental varnish composition according to claim 38 ,
wherein the organic coloring agent is one or more selected from the group consisting of an azo pigment, a phthalocyanine pigment, and a polycyclic pigment.
40 . The dental varnish composition according to claim 37 ,
wherein the coloring agent is an inorganic coloring agent.
41 . The dental varnish composition according to claim 40 ,
wherein the inorganic coloring agent is one or more selected from the group consisting of titanium oxide, rutile titanium, anatase titanium, zinc oxide, aluminum oxide, zinc sulfide, yellow iron oxide, ultramarine blue, red iron oxide, carbon black, and graphite.
42 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises a sweetener.
43 . The dental varnish composition according to claim 42 ,
wherein the sweetener is one or more selected from the group consisting of xylitol, maltitol, aspartame, sorbitol, saccharin sodium, sucralose, reduced palatinose, palatinose, mannitol, erythritol, and cyclodextrin.
44 . The dental varnish composition according to claim 23 ,
wherein the dental varnish composition further comprises a viscosity modifier.
45 . The dental varnish composition according to claim 44 ,
wherein the viscosity modifier is one or more selected from the group consisting of cellulose derivative, polyacrylic acid, vinyl alcohol, xanthan gum, silica, polyamide resin, and polyvinylpyrrolidone.Join the waitlist — get patent alerts
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