Delivery systems

Abstract

Methods for manufacturing drug delivery systems are provided. The drug delivery systems may include a substrate coated with at least one polymer and at least one active compound. The substrate may include yarns, yarn precursors, threads, filaments, fibers, and/or other suitable substrates. The methods may include disposing a solution including a monomer and an active compound on the substrate. The methods may also include exposing the solution and the substrate to UV light to initiate polymerization of the solution.

The invention claimed is: 
     
         1 . A machine-washable, reusable textile comprising:
 a yarn, wherein the yarn comprises a polymer comprising a biologically beneficial active compound;   wherein the machine-washable, reusable textile retains an effective amount of the biologically beneficial active compound for releasing the biologically beneficial active compound to skin of a subject after at least 5 wash cycles.   
     
     
         2 . The machine-washable, reusable textile of  claim 1 , wherein the yarn includes an air-covered yarn. 
     
     
         3 . The machine-washable, reusable textile of  claim 1 , wherein the polymer is a hydrophobic polymer. 
     
     
         4 . The machine-washable, reusable textile of  claim 1 , wherein the polymer is cross-linked. 
     
     
         5 . The machine-washable, reusable textile of  claim 1 , wherein the yarn is imbibed with the polymer. 
     
     
         6 . The machine-washable, reusable textile of  claim 1 , wherein the yarn comprising the polymer is in a knitted relationship or a woven relationship with yarn which does not include the polymer. 
     
     
         7 . The machine-washable, reusable textile of  claim 6 , wherein the yarn which does not include the polymer exhibits a greater elasticity than the yarn comprising the polymer. 
     
     
         8 . The machine-washable, reusable textile of  claim 1 , wherein the machine-washable, reusable textile is incorporated into a garment, bedding, toweling, a bandage, a wound dressing, an orthopedic device, protective athletic equipment, a furniture covering, a leather grip, a tight-fitting fabric, a sock, a hat, a face mask, a scarf, an undergarment, a skin guard, a wrist band, an arm band, a knee pad, a bra, a pair of tights, a pair of leggings, an athletic supporter, a robe, a neck band, a head band, a pair of gloves, a diaper, or a joint brace. 
     
     
         9 . The machine-washable, reusable textile of  claim 1 , wherein the machine-washable, reusable textile loses less than 25% of the biologically beneficial active compound in a wash cycle. 
     
     
         10 . A machine-washable, reusable textile comprising:
 a yarn, wherein the yarn includes a biologically beneficial active compound, wherein the yarn which includes the biologically beneficial active compound is in a knitted or woven relationship with yarn which does not include the biologically beneficial active compound;   wherein the machine-washable, reusable textile retains an effective amount of the biologically beneficial active compound for releasing the biologically beneficial active compound to skin of a subject after a wash cycle.   
     
     
         11 . The machine-washable, reusable textile of  claim 10 , wherein the biologically beneficial active compound includes a crosslinked, hydrophobic polymer. 
     
     
         12 . The machine-washable, reusable textile of  claim 10 , wherein the yarn which does not include the biologically beneficial active compound exhibits a greater elasticity than the yarn which includes the biologically beneficial active compound. 
     
     
         13 . The machine-washable, reusable textile of  claim 10 , wherein the machine-washable, reusable textile is incorporated into a garment, bedding, toweling, a bandage, a wound dressing, an orthopedic device, protective athletic equipment, a furniture covering, a leather grip, a tight-fitting fabric, a sock, a hat, a face mask, a scarf, an undergarment, a skin guard, a wrist band, an arm band, a knee pad, a bra, a pair of tights, a pair of leggings, an athletic supporter, a robe, a neck band, a head band, a pair of gloves, a diaper, or a joint brace. 
     
     
         14 . The machine-washable, reusable textile of  claim 10 , wherein the machine-washable, reusable textile loses less than 25% of the biologically beneficial active compound in the wash cycle. 
     
     
         15 . The machine-washable, reusable textile of  claim 10 , wherein the machine-washable, reusable textile retains the effective amount of the biologically beneficial active compound for releasing the biologically beneficial active compound to skin of the subject after five wash cycles. 
     
     
         16 . A machine-washable, reusable textile comprising:
 a textile including a cross-linked hydrophobic polymer comprising a biologically beneficial active compound;   wherein the machine-washable, reusable textile retains an effective amount of the biologically beneficial active compound for releasing the biologically beneficial active compound to skin of a subject after a wash cycle.   
     
     
         17 . The machine-washable, reusable textile of  claim 16 , wherein the biologically beneficial active compound includes a crosslinked, hydrophobic polymer. 
     
     
         18 . The machine-washable, reusable textile of  claim 16 , wherein the textile includes a yarn. 
     
     
         19 . The machine-washable, reusable textile of  claim 16 , wherein the machine-washable, reusable textile is incorporated into a garment, bedding, toweling, a bandage, a wound dressing, an orthopedic device, protective athletic equipment, a furniture covering, a leather grip, a tight-fitting fabric, a sock, a hat, a face mask, a scarf, an undergarment, a skin guard, a wrist band, an arm band, a knee pad, a bra, a pair of tights, a pair of leggings, an athletic supporter, a robe, a neck band, a head band, a pair of gloves, a diaper, or a joint brace. 
     
     
         20 . The machine-washable, reusable textile of  claim 16 , wherein the machine-washable, reusable textile loses less than 25% of the biologically beneficial active compound in the wash cycle.