Composition for prevention or treatment of neurological or mental disorders comprising extracellular vesicles derived from lactobacillus paracasei

Abstract

Provided are a method for preventing, improving, or treating a neurological disorder, mental disorder, senescence, or symptoms thereof, comprising administering to a subject in need thereof vesicles derived from Lactobacillus paracasei as an active ingredient, and a pharmaceutical or functional food composition comprising the vesicles

1 .- 17 . (canceled) 
     
     
         18 . A method for alleviating or treating a mental disorder, the method comprising administering a composition comprising vesicles derived from  Lactobacillus paracasei  as an active ingredient to an individual in need thereof. 
     
     
         19 . The method of  claim 18 , wherein the mental disorder is selected from the group consisting of anxiety disorders, post-traumatic stress disorder (PTSD), panic disorder, depression, autism spectrum disorder, attention deficit/hyperactivity disorder (ADHD), schizophrenia, and a combination thereof. 
     
     
         20 . The method of  claim 18 , wherein the vesicles have an average diameter of 10 to 1000 nm. 
     
     
         21 . The method of  claim 18 , wherein the vesicles are isolated from a  Lactobacillus paracasei  culture solution. 
     
     
         22 . The method of  claim 18 , wherein the vesicles are isolated from a food composition comprising  Lactobacillus paracasei.    
     
     
         23 . The method of  claim 18 , wherein the vesicles are naturally or artificially secreted from  Lactobacillus paracasei.    
     
     
         24 . The method of  claim 18 , wherein the composition is a pharmaceutical composition. 
     
     
         25 . The method of  claim 18 , wherein the composition is a food composition. 
     
     
         26 . The method of  claim 18 , wherein the composition is an inhalation composition.