Methods Of Administering High Concentrations Of Nitric Oxide

Abstract

Described are methods of administering therapeutic gases comprising high concentrations of nitric oxide, particularly concentrations above 2,000 ppm. The therapeutic gas may be administered at a certain dosing rate, such as less than 166 micrograms of nitric oxide per second. Also described are methods of administering a therapeutic gas comprising nitric oxide to a patient, wherein a dose of nitric oxide is administered from a portable device that includes a delivery system and a mini-cylinder. Methods of intermittent administration of nitric oxide pulses are also described.

What is claimed is: 
     
         1 . A method of administering nitric oxide (NO), the method comprising administering a gas comprising NO from a cylinder having a NO concentration greater than 2,000 ppm NO, wherein the gas comprising NO is administered at a dosing rate less than or equal to 166 μg NO per second.