Intranasal drug delivery device, system, and process

Abstract

Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

1 - 22 . (canceled) 
     
     
         23 . A fluid delivery device for delivering fluid to a nasal cavity of a subject, the device comprising:
 (a) a dispensing tip for dispensing a fluid, the dispensing tip coupled to a shot chamber for containing the fluid; and   (b) an actuator operatively coupled to the shot chamber such that upon actuation of the actuator the fluid flows from the shot chamber and out of the dispensing tip; wherein the compliant dispensing tip comprises a nostril stop that is configured to: (I) limit depth of insertion of the dispensing tip into a nasal cavity of the subject; and (II) provide feedback to a user when the dispensing tip reaches a location proximate to an olfactory region in the nasal cavity of the subject, wherein the dispensing tip defines a channel therein, wherein the device is configured for dispensing the fluid therefrom as a laminar flow.   
     
     
         24 . The fluid delivery device of  claim 23 , wherein the dispensing tip comprises at least one cannula. 
     
     
         25 . The fluid delivery device of  claim 23 , wherein the actuator is loaded by a spring. 
     
     
         26 . The fluid delivery device of  claim 23 , wherein the spring is in alignment with a plunger. 
     
     
         27 . The fluid delivery device of  claim 26 , wherein upon actuation of the device the plunger exerts pressure on the shot chamber and forces the fluid flow out of the shot chamber. 
     
     
         28 . The fluid delivery device of  claim 23 , wherein the fluid delivery device is: hand held, useable with a single hand, designed for ambidextrous use, promotes proper positioning in the nasal cavity, requires only a single user action to deliver a primed dose, prevents dispensing partial of doses, or combinations thereof. 
     
     
         29 . The fluid delivery device of  claim 23 , wherein the device is configured to deliver multiple doses. 
     
     
         30 . The fluid delivery device of  claim 23 , wherein dispensing the fluid therefrom as a laminar flow comprises a discreet liquid slug. 
     
     
         31 . The fluid delivery device of  claim 30 , wherein the discreet liquid slug is configured for maximizing dose delivery to a flat narrow section of the nasal cavity leading up to the olfactory region. 
     
     
         32 . The fluid delivery device of  claim 23 , further comprising a housing, wherein the housing defines an outer body of the device. 
     
     
         33 . The fluid delivery device of  claim 23 , wherein the housing comprises a dispensing opening. 
     
     
         34 . The fluid delivery device of  claim 23 , wherein the dispensing tip is biased to follow the patient's septum. 
     
     
         35 . The fluid delivery device of  claim 23 , wherein the dispensing tip conforms to the anterior aspect of the intranasal passage. 
     
     
         36 . The fluid delivery device of  claim 23 , further comprising a removable reservoir comprising the fluid. 
     
     
         37 . The fluid delivery device of  claim 27 , wherein the reservoir comprises a non-air interface mechanically pressurized fluid reservoir to enable dosing independent of orientation. 
     
     
         38 . The fluid delivery device of  claim 27 , wherein the reservoir comprises a disposable reservoir. 
     
     
         39 . The fluid delivery device of  claim 27 , wherein the reservoir comprises a refillable reservoir.