Particle filtration device and method of particle filtration

Abstract

A particle filtration device according to an embodiment of the present invention as a particle filtration device of a lab-on-disk of a rotation type includes: a filtration film that separates particles by filtering a sample; a main chamber connected to the inlet surface of the filtration film and supplying the sample to the inlet surface of the filtration film; an outlet chamber that is connected to the outlet surface of the filtration film and accommodates the filtration fluid from which particles are separated while passing through the filtration film; and a waste fluid chamber connected to the outlet chamber and storing the filtration fluid, wherein the particle filtration device includes a first flow path that connects between the outlet chamber and the waste fluid chamber, and a second flow path that connects between the outlet chamber and the waste fluid chamber but is positioned farther from the center of the lab-on-disk than the first flow path.

What is claimed is: 
     
         1 . A particle filtration device of a lab-on-disk of a rotation type, comprising:
 a filtration film that separates particles by filtering a sample;   a main chamber connected to the inlet surface of the filtration film and supplying the sample to the inlet surface of the filtration film;   an outlet chamber that is connected to the outlet surface of the filtration film and accommodates the filtration fluid from which particles are separated while passing through the filtration film; and   a waste fluid chamber connected to the outlet chamber and storing the filtration fluid,   wherein the particle filtration device includes a first flow path that connects between the outlet chamber and the waste fluid chamber, and a second flow path that connects between the outlet chamber and the waste fluid chamber but is positioned farther from the center of the lab-on-disk than the first flow path.   
     
     
         2 . The particle filtration device of  claim 1 , further comprising 
 a first valve that opens and closes the first flow path on the first flow path.   
     
     
         3 . The particle filtration device of  claim 1 , further comprising 
 a second valve that opens and closes the second flow path on the second flow path.   
     
     
         4 . The particle filtration device of  claim 1 , wherein 
 the outlet chamber includes a first vent hole connected to the first flow path and a second vent hole connected to the second flow path.   
     
     
         5 . The particle filtration device of  claim 1 , wherein 
 the main chamber and the outlet chamber are positioned at the upper part and the lower part of the filtration film, respectively, with the filtration film in in a direction perpendicular to the direction away from the center of the lab-on- disk.   
     
     
         6 . The particle filtration device of  claim 1 , wherein 
 the waste fluid chamber is positioned away from the center of the lab-on-disk relative to the filtration film.   
     
     
         7 . The particle filtration device of  claim 1 , wherein 
 the first flow path is a path for filling the outlet chamber with the priming water.   
     
     
         8 . A particle filtration method using a particle filtration device of a lab-on-disk a rotation type,
 wherein the particle filtration device includes a filtration film that separates particles by filtering a sample, comprising: 
 a main chamber connected to the inlet surface of the filtration film and supplying the sample to the inlet surface of the filtration film; 
 an outlet chamber that is connected to the outlet surface of the filtration film and accommodates the filtration fluid from which particles are separated through the filtration film; and 
 a waste fluid chamber connected to the outlet chamber and storing the filtration fluid, and 
 the particle filtration device includes a first flow path that connects between the outlet chamber and the waste fluid chamber, and a second flow path that connects between the outlet chamber and the waste fluid chamber but is positioned farther from the center of the lab-on-disk than the first flow path, and 
 before filtrating the sample by injecting the sample to the main chamber, 
 the particle filtration method includes filling priming water to the outlet chamber. 
   
     
     
         9 . The particle filtration method of  claim 8 , wherein 
 the filling of the priming water to the outlet chamber includes: 
 injecting the priming water to the main chamber; and 
 rotating the particle filtration device to fill the priming water to the outlet chamber in a state that the first flow path is opened and the second flow path is closed. 
   
     
     
         10 . The particle filtration method of  claim 9 , wherein 
 the filtrating of the sample includes   rotating the particle filtration device to filtrate the sample in a state that the first valve is closed and the second valve is opened after injecting the sample to the main chamber.   
     
     
         11 . The particle filtration method of  claim 10 , further comprising,
 after the filtrating of the sample,   rotating the particle filtration device to remove the priming water from the outlet chamber in a state that the first valve and the second valve are both opened.   
     
     
         12 . The particle filtration method of  claim 10 , wherein 
 the rotation speed of the particle filtration device in the filling of the priming water is slower than the rotation speed of the particle filtration device in the filtering of the sample.   
     
     
         13 . The particle filtration method of  claim 8 , wherein 
 the priming water in the outlet chamber is filled to be in contact with the filtration film by the filling of the priming water.