Green tea flower formulation for weight management

Abstract

The invention is directed to a composition formulated from green tea flower and methods for making and using the composition in the management of body weight.

1 . A method of promoting a healthy body weight in a subject, comprising administering to the subject a composition comprising an effective amount of green tea flower extract. 
     
     
         2 . The method of  claim 1 , wherein said extract has an IC50 value of about 120 μg/mL for pancreatic lipase in vitro. 
     
     
         3 . The method of  claim 1 , wherein said extract has an IC50 value of about 199 μg/mL for alpha amylase in vitro. 
     
     
         4 . The method of  claim 1 , wherein said extract has an IC50 value of about 43 μg/mL for lipid peroxidation in vitro. 
     
     
         5 . The method of  claim 1 , wherein said extract has an IC50 of about 41 μg/mL as determined by DPPH radical scavenging assay. 
     
     
         6 . The method of  claim 1 , wherein administering said composition reduces body weight in said subject. 
     
     
         7 . The method of  claim 1 , wherein administering said composition prevents or inhibits weight gain in said subject. 
     
     
         8 . The method of  claim 1 , wherein administering said composition maintains said subject's body weight. 
     
     
         9 . The method of  claim 1 , wherein administering said composition reduces body fat in said subject. 
     
     
         10 . The method of  claim 1 , wherein administering said composition prevents or inhibits body fat gain in said subject. 
     
     
         11 . The method of  claim 1 , wherein said subject is overweight. 
     
     
         12 . The method of  claim 1 , wherein said subject is obese. 
     
     
         13 . The method of  claim 1 , wherein said extract is administered at a dose of about 50 mg per kilogram of bodyweight, about 100 mg per kilogram of bodyweight, about 150 mg per kilogram of bodyweight, or combinations thereof. 
     
     
         14 . (canceled) 
     
     
         15 . The method of  claim 1 , wherein said composition is administered daily, weekly, monthly, or combinations thereof. 
     
     
         16 . The method of  claim 1 , wherein said composition is administered in a form selected from the group consisting of a powder, liquid, pill, tablet, pellet, granule, capsule, soluble film, solution, spray, syrup, linctus, lozenge, pastille, chewing gum, chew, paste, vapor, suspension, emulsion, ointment, cream, lotion, foam, liniment, gel, drop, topical patch, buccal patch, bead, gummy, gel, sol, injection, and combinations thereof. 
     
     
         17 . The method of  claim 1 , wherein said composition further comprises at least one of a vitamin, mineral, amino acid, protein, carbohydrate, lipid, fatty acid, excipient, pharmaceutical carrier, bulking agent, binding agent, caffeine, flavoring, sweetener, and preservative. 
     
     
         18 . The method of  claim 1 , wherein said composition is selected from the group consisting of a food, snack, nutritional supplement, dietary supplement, food supplement, beverage, and combination thereof. 
     
     
         19 . The method of  claim 1 , wherein said composition is administered systemically. 
     
     
         20 . The method of  claim 1 , wherein said composition is administered by a route selected from the group consisting of orally, buccally, sub-lingually, and combinations thereof. 
     
     
         21 . (canceled) 
     
     
         22 . The method of  claim 1 , wherein said subject is a human.