Biocompatible materials

Abstract

A resin composition, the resin composition including a prepolymer ( 209 ) and optionally one or more diluent(s) ( FIG. 3 A ), the prepolymer ( 209 ) including repeating units having at least one carbonate linkage and at least one unsaturated side-chain, the at least one optional diluent(s) comprising at least one unsaturated side-chain, with either or both of the prepolymer ( 209 ) and the at least one optional diluent(s) including at least one O=C-N linkage, preferably a urethane linkage.

1 - 33 . (canceled) 
     
     
         34 . A 3D printed device, the device comprising a shape memory polymer, the shape memory polymer being a cross-linked polymer and being able to undergo a morphological change from a first state to a second state upon induction by an external stimulus, the cross-linked polymer having a dry modulus value of from 1 MPa and 2 GPa, and a glass transition temperature of between -10° C. and 150° C., the 3D printed device being porous and having pores in the size range of 200 µm to 1500 µm. 
     
     
         35 . The 3D printed device according to claim  1 , wherein the glass transition temperature of the crossed linked polymer is between 20 to 80° C., for example between 35 to 45° C. such as between 36.5 and 37.5° C. 
     
     
         36 . The 3D printed device according to claim  1 , wherein the porosity of the crosslinked polymer is from 0.7 to 0.95. 
     
     
         37 . The 3D printed device according to claim  1 , wherein the crosslinked polymer comprises at least one carbonate linkage. 
     
     
         38 . The 3D printed device according to claim  1 , wherein the crosslinked polymer comprises at least one O=C-N linkage. 
     
     
         39 . The 3D printed device according to claim  5 , wherein the O=C-N linkage is selected from a urethane or urea moiety. 
     
     
         40 . The 3D printed device according to claim  1 , wherein the crosslinked polymer is fabricated from a resin composition comprising a prepolymer, wherein the prepolymer comprises repeating units having at least one carbonate linkage and at least one unsaturated side chain. 
     
     
         41 . The 3D printed device according to claim  7 , wherein the resin composition further comprises at least one diluent, and wherein one of the prepolymer or the diluent comprises at least one O=C-N linkage. 
     
     
         42 . The 3D printed device according to claim  1 , wherein the cross-linked polymer is degradable into degradation products upon exposure to water, acid, base, heat, enzymes, solvent, and/or oxidisers. 
     
     
         43 . The 3D printed device according to claim  1 , wherein the device is selected from a medical device, an implantable medical device, or a tissue scaffold. 
     
     
         44 . A 3D printed crosslinked polymer, the polymer comprising a carbonate linkage and an O=C-N linkage. 
     
     
         45 . The 3D printed crosslinked polymer according to claim  11 , wherein the O=C-N linkage is selected from a urethane or urea bond. 
     
     
         46 . The 3D printed crosslinked polymer according to claim  11 , wherein crosslinked polymer is porous and has pores in the size range of 200 µm to 1500 µm. 
     
     
         47 . The 3D printed crosslinked polymer according to claim  11 , wherein the porosity of the crosslinked polymer is from 0.7 to 0.95. 
     
     
         48 . The 3D printed crosslinked polymer according to claim  11 , wherein the a glass transition temperature of the crosslinked polymer is between -10° C. and 150° C. 
     
     
         49 . The 3D printed crosslinked polymer according to claim  11 , wherein the dry modulus value of the crosslinked polymer is from 1 MPa and 2 GPa. 
     
     
         50 . The 3D printed crosslinked polymer according to claim  11 , which is able to undergo a morphological change from a first state to a second state upon induction by an external stimulus. 
     
     
         51 . The 3D printed crosslinked polymer according to claim  11 , wherein the cross-linked polymer is degradable into degradation products upon exposure to water, acid, base, heat, enzymes, solvent, and/or oxidisers. 
     
     
         52 . The 3D printed crosslinked polymer according to claim  11 , wherein the cross-linked polymer is a device selected from a medical device, an implantable medical device, or a tissue scaffold. 
     
     
         53 . A 3D printed device, the device comprising a shape memory polymer, the shape memory polymer being a cross-linked polymer and being able to undergo a morphological change from a first state to a second state upon induction by an external stimulus, the cross-linked polymer comprising a carbonate moiety and an O=C-N linkage.