US2023324383A1PendingUtilityA1

Monoclonal antibodies with specificity for fetal erythroid cells

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Assignee: KELLBENX INCORPORATEDPriority: Mar 31, 2004Filed: Nov 18, 2022Published: Oct 12, 2023
Est. expiryMar 31, 2024(expired)· nominal 20-yr term from priority
Inventors:Christiane HollmannSilke ZimmermannStefan StachelhausWinfried Albert
G01N 33/56966G01N 33/5094G01N 33/577G01N 33/80C07K 16/28Y10T436/25375Y10T436/25125C07K 2317/14G01N 2333/70582G01N 2469/10
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Claims

Abstract

The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The inventive monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A fluorescently labeled monoclonal antibody, wherein the antibody is produced by the hybridoma 4B9 deposited with the Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH under accession number DSM ACC 2666.

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