Oral Care Compositions

Abstract

In one aspect, the present disclosure relates to oral care compositions comprising a source of zinc, a fluoride source, a zwitterionic surfactant and a taurate surfactant. In one aspect the compositions of the disclosure can be used for the treatment or reduction of erosive tooth demineralization, gingivitis, plaque, and dental caries. In one aspect the oral care composition includes zinc citrate, zinc oxide, arginine, cocamidopropyl betaine and at least one taurate surfactant (e.g., sodium methyl cocoyl taurate).

1 . An oral care composition comprising:
 A source of zinc ions,   A source of fluoride;   An effective amount of a zwitterionic surfactant; and   An effective amount of a taurate surfactant, wherein the taurate surfactant is represented by Formula (1):
                     
   wherein R 1  is a saturated or unsaturated, straight or branched alkyl chain with 6 to 18 C atoms R 2  is H or methyl, and M +  is H, sodium, or potassium.   
     
     
         2 . The oral care composition of  claim 1 , wherein the R 1  is a saturated or unsaturated, straight or branched alkyl chain with 8 to 14 C atoms. 
     
     
         3 . The oral care composition of  claim 1 , wherein the taurate surfactant comprises one or more surfactant selected from the group consisting of:
 potassium cocoyl taurate, potassium methyl cocoyl taurate, sodium caproyl methyl taurate, sodium cocoyl taurate, sodium lauroyl taurate, sodium methyl cocoyl taurate, sodium methyl lauroyl taurate, sodium methyl myristoyl taurate, sodium methyl oleoyl taurate, sodium methyl palmitoyl taurate, sodium methyl stearoyl taurate, and combinations thereof.   
     
     
         4 . The oral care composition of  claim 1 , wherein the taurate surfactant comprises one or more surfactant selected from the group consisting of:
 sodium lauroyl methyl taurate (or sodium methyl lauroyl taurate), sodium methyl cocoyl taurate, and combinations thereof.   
     
     
         5 . The oral care composition of  claim 1 , wherein the taurate surfactant comprises sodium methyl cocoyl taurate. 
     
     
         6 . The oral care composition of  claim 1 , wherein:
 the taurate surfactant is present in an amount of from 0.25% to 5% by weight of the composition;   the amount of the fluoride ion source is in an amount from 0.01% to 5% by weight, relative to the weight of the oral care composition;   the amount of the fluoride ion source is in an amount from 0.01% to 5% by weight, relative to the weight of the oral care composition, and is selected from the group consisting of: sodium fluoride, potassium fluoride, calcium fluoride, zinc fluoride, zinc ammonium fluoride, lithium fluoride, ammonium fluoride, stannous fluoride, stannous fluorozirconate, sodium monofluorophosphate, potassium monofluorophosphate, laurylamine hydrofluoride, diethylaminoethyloctoylamide hydrofluoride, didecyldimethylammonium fluoride, cetylpyridinium fluoride, dilaurylmorpholinium fluoride, sarcosine stannous fluoride, glycine potassium fluoride, glycine hydrofluoride, amine fluorides, and combinations thereof.   
     
     
         7 . (canceled) 
     
     
         8 . (canceled) 
     
     
         9 . The oral care composition of  claim 6 , wherein the fluoride ion source comprises sodium fluoride or stannous fluoride. 
     
     
         10 . (canceled) 
     
     
         11 . The oral care composition of  claim 1 , wherein the source of zinc comprises a zinc salt selected from zinc citrate, zinc oxide, zinc lactate, zinc pyrophosphate, zinc sulfate, zinc phosphate, zinc chloride and combinations thereof. 
     
     
         12 . The oral care composition of  claim 11 , wherein the source of zinc comprises zinc oxide and zinc citrate. 
     
     
         13 . The oral care composition of  claim 12 , wherein the ratio of the wt.% amount of zinc oxide to zinc citrate is from 1.5:1 to 4.5:1. 
     
     
         14 . The oral care composition of  claim 12 , wherein the zinc citrate is in an amount of from 0.25% to 1.0% by wt. and zinc oxide may be present in an amount of from 0.75% to 1.25% by wt. based on the weight of the oral care composition. 
     
     
         15 . The oral care composition of  claim 1 , wherein the source of zinc comprises zinc phosphate. 
     
     
         16 . The oral care composition of  claim 1 , comprising an amino acid, wherein the amino acid is a basic amino acid. 
     
     
         17 . The oral care composition of  claim 16 , wherein the basic amino acid comprises arginine or lysine, and wherein the arginine or lysine is present in an amount corresponding to 1% to 15% by wt., wherein the weight of the basic amino acid is calculated as free form. 
     
     
         18 . The oral care composition of  claim 1 , wherein the zwitterionic surfactant is a betaine zwitterionic surfactant. 
     
     
         19 . The oral care composition of  claim 18 , wherein the betaine zwitterionic surfactant is a C8-C16 aminopropyl betaine. 
     
     
         20 . The oral care composition of  claim 1  wherein the C8-C16 aminopropyl betaine is cocamidopropyl betaine. 
     
     
         21 . The oral care composition of  claim 1 , wherein the composition comprises:
 Zinc phosphate from 0.5 - 4% by wt.;   Stannous fluoride 0.2% - 2% by wt.;   Sodium methyl cocoyl taurate 0.5% - 4% by wt.;   Cocamidopropyl Betaine 0.5% - 5% by wt.; and   An orally acceptable carrier; or   Zinc oxide from 0.5% - 1.5% by wt.;   Zinc citrate from 0.25% - 0.75% by wt.;   Sodium fluoride or Stannous Fluoride or Sodium monofluorophosphate;   Sodium methyl cocoyl taurate from 0.5% - 4% by wt.;   Cocamidopropyl Betaine from 0.5% - 5% by wt.; and   An orally acceptable carrier; or   Zinc oxide from 0.5% - 1.5% by wt.;   Zinc citrate from 0.25% - 0.75% by wt.;   Arginine from 0.5% - 3% by wt.;   Sodium fluoride or Sodium monofluorophosphate;   Sodium methyl cocoyl taurate from 0.5% - 4% by wt.;   Cocamidopropyl Betaine from 0.5% - 5% by wt.; and   An orally acceptable carrier.   
     
     
         22 . (canceled) 
     
     
         23 . (canceled) 
     
     
         24 . A method of treatment or prophylaxis of erosive tooth demineralization, gingivitis, plaque, and/or dental caries, the method comprising the application to the oral cavity of a person in need thereof the oral care composition according to  claim 1 . 
     
     
         25 . (canceled)