Intelligent Bioelectric Module for Use with Drug Delivery System

Abstract

An intelligent bioelectric module for use with a drug delivery system has a case and a set of at least two electrodes in electrical communication with a detection surface of the case. The case is configured so that, in use, the detection surface comes into electrical communication with (i) a second surface of the delivery system when a first surface of the delivery system has been put into contact with a tissue surface of a human or animal subject or (ii) the tissue surface that is adjacent to a portion contacted by the first surface of the delivery system or (iii) both the second surface and the tissue surface.

What is claimed is: 
     
         1 . A bioelectric device for controlled drug delivery to a patient comprising:
 a. a case;   b. a controlled release drug delivery system disposed in the case and configured to receive by a mode selected from the group consisting of adherence, attachment, insertion, and combinations thereof, a drug, and to deliver the drug to the patient;   c. a set of microprocessors disposed in the case;   d. a memory module disposed in the case and coupled to the set of microprocessors;   e. a set of sensors (i) selected from the group consisting of accelerometer, inertial motion sensor, ambient temperature sensor, ambient light sensor, skin temperature sensor, skin conductance sensor, skin hydration sensor, heart rate sensor, blood pressure sensor, blood gas sensor, metabolic marker sensor, drug sensor and combinations thereof; (ii) disposed in the case, (iii) configured to sense receiving of the drug by the drug delivery platform; (iv) further configured to provide physiological data of the patient to the set of microprocessors; (v) coupled to the set of microprocessors, the set of microprocessors configured to monitor delivery of the drug;   f. a communication module disposed in the case and coupled to the set of microprocessors, configured to transmit the physiological data to a server; and   g. a power module disposed in the case and coupled to the set of microprocessors;   wherein processing of the physiological data, to identify an item selected from the group consisting of a disease signature and a therapeutic signature and combinations thereof, is achieved by a computing facility selected from the group consisting of the set of microprocessors, the server, and combinations thereof.   
     
     
         2 . A method of personalizing treatment using a bioelectric device according to  claim 1  comprising:
 a. detecting placement of the bioelectric device on a body of the patient; 
 b. delivering the drug through the bioelectric device; 
 c. recording the physiological data; 
 d. transmitting the physiological data to a server; 
 e. receiving instructions at the bioelectric device, from the server, for adjustments to the drug delivery. 
 
     
     
         3 . A method of personalizing treatment using a set of bioelectric devices according to  claim 1  comprising:
 a. detecting automatically when at least one patient is wearing at least one bioelectric device; 
 b. receiving physiological data from the at least one bioelectric device; 
 c. receiving parameters from the at least one bioelectric device including at least one parameter selected from the group consisting of device ID, patient ID, location, time, and date; 
 d. receiving patient and population baseline data from at least one database; 
 e. analyzing the received physiological data, patient data, and population baseline data; 
 f. generating at least one recommendation for individualizing therapeutics based on the analysis; 
 g. providing a report about the at least one patient's health information and individualized therapy via a web portal. 
 
     
     
         4 . The bioelectric device of  claim 1 , wherein the set of sensors comprises a set of inertial motion sensors, the set of inertial motion sensors selected from the group consisting of a 3-axis accelerometer, a 3-axis gyroscope, a 3-axis magnetometer, and combinations of the foregoing. 
     
     
         5 . The bioelectric device of  claim 4 , wherein the drug is suitable for treatment of neurological disorders. 
     
     
         6 . The bioelectric device of  claim 5 , wherein the bioelectric device is configured to tailor a dose and rate of drug delivery based on inertial motion measured by the set of inertial motion sensors. 
     
     
         7 . The bioelectric device of  claim 1 , wherein the drug is selected for treatment of motion disorders. 
     
     
         8 . The bioelectric device of  claim 1 , wherein the drug is selected for treatment of sleep disorders. 
     
     
         9 . The bioelectric device of  claim 1 , wherein the bioelectric device is configured to be controlled remotely. 
     
     
         10 . The bioelectric device of  claim 1 , wherein the device is configured to synchronize drug delivery with biological signals of the patient. 
     
     
         11 . The bioelectric device of  claim 1 , wherein the set of sensors is further selected from the group consisting of a blood pressure sensor, a skin temperature sensor, an ambient light sensor, an inertial motion sensor, and combinations thereof, wherein the bioelectric device is configured to tailor a dose and rate of drug delivery based on a parameter selected from the group consisting of blood pressure, skin temperature, ambient light, inertial motion, and combinations thereof.
 The bioelectric device of  claim 1 , wherein the communication module is configured to connect to a cloud network.