Devices, systems, and methods for monitoring and treatment of injuries

Abstract

Provided herein are medical devices, systems, and methods for monitoring and treating injuries, diseases, or other conditions in patients. The medical devices include body structures that comprise an imaging array, a stimulation array, and an electrode array. The medical devices are implantable in patients in some embodiments.

1 . A medical device, comprising:
 a body structure that comprises at least portions of at least three subassemblies, which subassemblies comprise at least one imaging array, at least one stimulation array, and at least one electrode array;   wherein the subassemblies are positionable within communication of at least one target location of a subject;   wherein the imaging array is structured to generate and/or capture images at least proximal to the target location of the subject when the imaging array is positioned within communication of the target location of the subject;   wherein the stimulation array is structured to administer at least a first therapy at least proximal to the target location of the subject when the stimulation array is positioned within communication of the target location of the subject;   wherein the electrode array is structured to administer at least a second therapy at least proximal to the target location of the subject when the electrode array is positioned within communication of the target location of the subject; and,   wherein the subassemblies are operably connected, or connectable, to at least one power source and/or at least one controller.   
     
     
         2 . The medical device of  claim 1 , wherein the body structure comprises at least one substantially rigid section and at least one substantially flexible section. 
     
     
         3 . The medical device of  claim 2 , wherein the substantially rigid section comprises at least one of the subassemblies. 
     
     
         4 . The medical device of  claim 1 , comprising at least two imaging arrays, wherein at least a first imaging array is configured to be positioned within communication of an uninjured site of the subject and at least a second imaging array is configured to be positioned within communication of an injured site of the subject. 
     
     
         5 - 18 . (canceled) 
     
     
         19 . The medical device of  claim 1 , wherein the target location comprises at least a portion of a spinal cord of the subject. 
     
     
         20 - 25 . (canceled) 
     
     
         26 . The medical device of  claim 1 , further comprising a position tracking system that tracks angular and torsional deflection of one or more of the subassemblies when the subassemblies are positioned within communication of the target location of the subject. 
     
     
         27 - 34 . (canceled) 
     
     
         35 . The medical device of  claim 1 , wherein the electrode array comprises a multi-layer polyimide/copper circuit having independent layers for transmit and receive modalities. 
     
     
         36 - 38 . (canceled) 
     
     
         39 . A system, comprising:
 a medical device, comprising:
 a body structure that comprises at least portions of at least three subassemblies, which subassemblies comprise at least one imaging array, at least one stimulation array, and at least one electrode array; 
 wherein the subassemblies are positionable within communication of at least one target location of a subject; 
 wherein the imaging array is structured to generate and/or capture images at least proximal to the target location of the subject when the imaging array is positioned within communication of the target location of the subject; 
 wherein the stimulation array is structured to administer at least a first therapy at least proximal to the target location of the subject when the stimulation array is positioned within communication of the target location of the subject; and, 
 wherein the electrode array is structured to administer at least a second therapy at least proximal to the target location of the subject when the electrode array is positioned within communication of the target location of the subject; 
   at least one power source operably connected to the subassemblies; and,   at least one controller operably connected to the subassemblies, which controller comprises, or is capable of accessing, computer readable media comprising non-transitory computer executable instructions which, when executed by at least one electronic processor, perform at least:
 generating and/or capturing images at least proximal to a target location of a subject using the imaging array; 
 administering at least a first therapy at least proximal to the target location of the subject using the stimulation array; and, 
 administering at least a second therapy at least proximal to the target location of the subject using the electrode array. 
   
     
     
         40 . The system of  claim 39 , wherein the non-transitory computer executable instructions comprise one or more machine learning algorithms that effectuate generating and/or capturing the images and/or administering the first and/or second therapies. 
     
     
         41 - 44 . (canceled) 
     
     
         45 . The system of  claim 39 , wherein the body structure comprises at least one substantially rigid section and at least one substantially flexible section. 
     
     
         46 . The system of  claim 45 , wherein the substantially rigid section comprises at least one of the subassemblies. 
     
     
         47 - 50 . (canceled) 
     
     
         51 . The system of  claim 39 , wherein the medical device comprises at least one wearable device comprising at least one breakout box that is operably connected, or connectable, to the medical device at least when the subassemblies are positioned within communication of the target location of the subject, wherein the breakout box is configured to receive data from the medical device and/or to transmit data to the medical device. 
     
     
         52 - 73 . (canceled) 
     
     
         74 . The system of  claim 39 , wherein the electrode array comprises a titanium nitride electrode surface conductor. 
     
     
         75 . The system of  claim 39 , wherein the electrode array comprises a multi-layer polyimide/copper circuit having independent layers for transmit and receive modalities. 
     
     
         76 . (canceled) 
     
     
         77 . (canceled) 
     
     
         78 . A computer readable media comprising non-transitory computer executable instruction which, when executed by an electronic processor perform at least:
 generating and/or capturing images at least proximal to a target location of a subject using at least one imaging array of a medical device that comprises a body structure that comprises at least portions of the imaging array;   administering at least a first therapy at least proximal to the target location of the subject using at least one stimulation array of the medical device that comprises the body structure that comprises at least portions of the stimulation array; and,   administering at least a second therapy at least proximal to the target location of the subject using at least one electrode array of the medical device that comprises the body structure that comprises at least portions of the electrode array.   
     
     
         79 . A method of providing medical care to a subject, the method comprising;
 generating and/or capturing images at least proximal to a target location of the subject using at least one imaging array of a medical device that comprises a body structure that comprises at least portions of the imaging array;   administering at least a first therapy at least proximal to the target location of the subject using at least one stimulation array of the medical device that comprises the body structure that comprises at least portions of the stimulation array; and,   administering at least a second therapy at least proximal to the target location of the subject using at least one electrode array of the medical device that comprises the body structure that comprises at least portions of the electrode array, thereby providing the medical care to the subject.   
     
     
         80 . The method of  claim 79 , wherein the body structure of the medical device comprises at least one substantially rigid section and at least one substantially flexible section. 
     
     
         81 . The method of  claim 80 , wherein the substantially rigid section comprises at least one of the subassemblies. 
     
     
         82 - 86 . (canceled) 
     
     
         87 . The method of  claim 79 , wherein the medical device comprises a belt that is worn by the subject. 
     
     
         88 . The method of  claim 79 , wherein the body structure is implantable in the subject. 
     
     
         89 - 121 . (canceled)