Compositions for Enhancing Bioavailability of Pharmaceuticals, Supplements and Ingested Substances

Abstract

The present invention relates to compositions and methods for enhancing bioavailability of health-promoting substances, such as pharmaceuticals and nutritional supplements. The subject invention utilizes an adjuvant composition comprising one or more microbial-produced biosurfactants and/or isoforms thereof, to enhance bioavailability of health-promoting substances and to reduce the effective dosage that is required.

What is claimed: 
     
         1 . A method for administering a health-promoting substance to a tissue in a subject, the method comprising administering, to the subject, an effective amount of a composition comprising a purified sophorolipid and said health-promoting substance; wherein said composition is administered to the subject via transdermal or cutaneous administration; and wherein said health promoting substance is selected from hydrating substances, anti-inflammatory compounds, vitamins, minerals, and nutrients. 
     
     
         2 . The method of  claim 1 , wherein the sophorolipid is present in the composition in critical micelle concentration (CMC). 
     
     
         3 . The method of  claim 1 , wherein the health-promoting substance is encapsulated in a nanocapsule formed by the sophorolipid. 
     
     
         4 . The method of  claim 1 , wherein the health promoting substance is vitamin, mineral, or nutrient. 
     
     
         5 . The method of  claim 1 , wherein at least 60% by weight of said purified sophorolipid is in an acidic form.