US2023406917A1PendingUtilityA1

Egg, fertilized egg, or embryo quality improving agent

Assignee: MPO INCPriority: Sep 26, 2016Filed: Sep 5, 2023Published: Dec 21, 2023
Est. expirySep 26, 2036(~10.2 yrs left)· nominal 20-yr term from priority
C07K 16/24C07K 16/2866C12N 5/0604G01N 33/6863G01N 33/689C12N 2501/998G01N 2333/521G01N 2800/36G01N 2800/7042A61P 15/08A61K 39/395A61P 15/00A61K 2039/505A61K 31/17C12N 2501/20G01N 33/5091C12N 2517/10C12N 5/0609
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Claims

Abstract

Object of the present invention is to provide means for improving the quality of preimplantation embryos deteriorated with age or the like. The present invention relates to an agent for improving the quality of an egg, a fertilized egg, and/or an embryo, including a substance that inhibits signal transmission from CXCL5.

Claims

exact text as granted — not AI-modified
1 - 7 . (canceled) 
     
     
         8 . A culture medium of an egg, a fertilized egg, and/or an embryo, comprising a substance that inhibits signal transmission from CXCL5. 
     
     
         9 . The culture medium according to  claim 8 , wherein the substance that inhibits signal transmission from CXCL5 is a substance that inhibits an interaction between CXCL5 and CXCR2. 
     
     
         10 . The culture medium according to  claim 9 , wherein the substance that inhibits an interaction between CXCL5 and CXCR2 is an anti-CXCL5 antibody or a fragment thereof, an anti-CXCR2 antibody or a fragment thereof, or a CXCR2 antagonist. 
     
     
         11 . The culture medium according to  claim 8 , wherein the culture medium is used for improving a quality of an egg, a fertilized egg, and/or an embryo. 
     
     
         12 . The culture medium according to  claim 11 , wherein the quality of an egg, a fertilized egg, and/or an embryo is deteriorated due to aging.

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