Method for testing drug response of cardiomyocytes

Abstract

A method for testing drug response of a cardiomyocyte, the method comprising: testing a response of the cardiomyocyte to an added drug in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less; or testing a response of the cardiomyocyte to an added drug immediately after placing the cardiomyocyte in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less.

1 - 3 . (canceled) 
     
     
         4 . A method for testing drug response of a cardiomyocyte, the method comprising:
 testing a response of the cardiomyocyte to an added drug in a culture medium contained in a container having an oxygen permeability; or   testing a response of the cardiomyocyte to an added drug immediately after placing the cardiomyocyte in a culture medium contained in a container having an oxygen permeability.   
     
     
         5 - 10 . (canceled) 
     
     
         11 . The method according to  claim 4 , wherein the method comprises:
 testing a response of the cardiomyocyte to an added drug in a culture medium contained in a container having an oxygen permeability.   
     
     
         12 . The method according to  claim 4 , wherein the container having an oxygen permeability includes a material having an oxygen permeability of 750 to 50000 ml·mm/m 2 ·day·atm. 
     
     
         13 . The method according to  claim 11 , wherein the container having oxygen permeability includes a material having an oxygen permeability of 750 to 50000 ml·mm/m 2 ·day·atm. 
     
     
         14 . The method according to  claim 4 , wherein the container having an oxygen permeability has a gas-permeable film on its bottom surface. 
     
     
         15 . The method according to  claim 11 , wherein the container having an oxygen permeability has a gas-permeable film on its bottom surface. 
     
     
         16 . The method according to  claim 4 , wherein the container having an oxygen permeability has a gas-permeable film on its bottom surface, the gas-permeable film having an oxygen permeability of 750 to 50000 ml·mm/m 2 ·day·atm. 
     
     
         17 . The method according to  claim 11 , wherein the container having an oxygen permeability has a gas-permeable film on its bottom surface, the gas-permeable film having an oxygen permeability of 750 to 50000 ml·mm/m 2 ·day·atm.