Fluid therapy method

Abstract

A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.

1 - 19 . (canceled) 
     
     
         20 . A fluid therapy system comprising:
 a urine output measurement device configured to measure a urine output of a patient;   a fluid administration device configured to infuse a fluid into the patient;   a controller configured to—
 receive a urine output of the patient based at least partially on the measured urine output, 
 control the infusion of the fluid during a first therapy period while (i) the patient is receiving a diuretic and/or (ii) the measured urine output of the patient is below a threshold urine output level; and 
 after the measured urine output exceeds the threshold urine output level, adjust the infusion of the fluid to achieve a negative fluid balance during a second therapy period following the first therapy period. 
   
     
     
         21 . The fluid therapy system of  claim 20  wherein the threshold urine output level is a rate of urine output. 
     
     
         22 . The fluid therapy system of  claim 20  wherein the threshold urine output level is a volume of urine output. 
     
     
         23 . The fluid therapy system of  claim 20  wherein the controller is further configured to administer a diuretic to the patient during the second therapy period. 
     
     
         24 . The fluid therapy system of  claim 20  wherein the fluid administration device adjusts the infusion of the fluid after the measured urine output is equal to or exceeds the threshold urine output level. 
     
     
         25 . The fluid therapy system of  claim 20  wherein adjusting the infusion of the fluid includes reducing a rate of the infusion to less than a current rate of the measured urine output. 
     
     
         26 . The fluid therapy system of  claim 20  wherein the controller is further configured to receive an input corresponding to the threshold urine output level, and wherein adjusting the infusion of the fluid includes adjusting the infusion of the fluid when the measured urine output is equal to or exceeds the threshold urine output level. 
     
     
         27 . The fluid therapy system of  claim 20  wherein the fluid is saline or an osmotic solute. 
     
     
         28 . The fluid therapy system of  claim 20  wherein the fluid is hypertonic saline. 
     
     
         29 . The fluid therapy system of  claim 20  wherein a rate of fluid infusion during the first therapy period and/or the second therapy period is determined based, at least in part, on the measured urine output. 
     
     
         30 . A fluid therapy system comprising:
 a urine output measurement device configured to measure a urine output of a patient;   a fluid administration device configured to administer fluid to the patient; and   a controller configured to—
 receive a urine output rate of the patient based on the measured urine output from the urine output measurement device, 
 control the fluid administration device to administer, during a first therapy period, fluid to the patient at one or more first rates, and 
 control the fluid administration device to administer, during a second therapy period, fluid to the patient at one or more second rates less than the measured urine output rate to induce a net fluid loss from the patient. 
   
     
     
         31 . The fluid therapy system of  claim 30  wherein the controller is configured to receive an input for setting a total fluid loss goal, and wherein controlling the fluid administration device to administer fluid to the patient at the one or more second rates includes controlling the fluid administration device to administer fluid to the patient at the one or more second rates at least until the net fluid loss from the patient reaches the total fluid loss goal. 
     
     
         32 . The fluid therapy system of  claim 30  wherein the urine output measurement device includes one or more devices configured to weigh a urine collection bag. 
     
     
         33 . The fluid therapy system of  claim 30  wherein the fluid administration device is configured to administer both fluid and a diuretic. 
     
     
         34 . The fluid therapy system of  claim 30  wherein the controller is configured to control the fluid administration device to automatically administer a diuretic at the start of therapy. 
     
     
         35 . The fluid therapy system of  claim 30  wherein the one or more first rates are equal to or approximately equal to the measured urine output rate. 
     
     
         36 . The fluid therapy system of  claim 30  wherein the controller is configured to control the fluid administration device to administer the fluid to the patient at the one or more first rates such that, during the first therapy period, the patient has little to no net fluid loss. 
     
     
         37 . The fluid therapy system of  claim 30  wherein the controller is configured to control the fluid administration device to administer the fluid to the patient at the one or more first rates to increase the urine output rate of the patient. 
     
     
         38 . The fluid therapy system of  claim 30  wherein the one or more second rates are less than the one or more first rates. 
     
     
         39 . The fluid therapy system of  claim 30  wherein the controller is configured to receive an input for setting a urine output rate desired threshold, and wherein the controller is configured to control the fluid administration device to administer the fluid at the one or more second rates after the urine output rate of the patient reaches the urine output rate desired threshold.