US2024000832A1PendingUtilityA1

Treatment and prevention of injury due to radiation exposure

Assignee: MEDESIS PHARMAPriority: Jul 6, 2018Filed: Sep 14, 2023Published: Jan 4, 2024
Est. expiryJul 6, 2038(~12 yrs left)· nominal 20-yr term from priority
A61K 33/32A61P 39/00A61K 9/1075A61K 47/10A61K 47/14A61K 47/24A61K 47/28A61K 33/04A61K 33/00A61K 33/30A61N 2005/1098
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Claims

Abstract

The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.

Claims

exact text as granted — not AI-modified
1 - 23 . (canceled) 
     
     
         24 . A reverse micellar system comprising at least a sterol, 50 to 90% of acylglycerol, 1 to 20% of lecithin, ethanol and water, and the weight ratio of lecithin to acylglycerol is from 0.05:1 to 0.4:1,
 wherein the reverse micellar system is free of a chelator,   wherein the reverse micellar system is free of cyano-bridged metal nanoparticles, and   wherein the reverse micellar system comprises at least 300 μg/g of manganese.   
     
     
         25 . The reverse micellar system of  claim 24 , comprising 5 to 15% lecithin. 
     
     
         26 . The reverse micellar system of  claim 24 , wherein the reverse micellar system is free of DTPA, bisphosphonates, Prussian blue, EDTA, Trientine, D-penicillamine, Deferoxamine, BAL, DMSA, DMPS, Phytic acid, Hydroxypyridonates (HOPO), mercaptoacetyltriglycine (MAG3), chelating peptides, derivatives thereof and combinations thereof. 
     
     
         27 . The reverse micellar system of  claim 25 , wherein the reverse micellar system is free of DTPA, bisphosphonates, Prussian blue, EDTA, Trientine, D-penicillamine, Deferoxamine, BAL, DMSA, DMPS, Phytic acid, Hydroxypyridonates (HOPO), mercaptoacetyltriglycine (MAG3), chelating peptides, derivatives thereof and combinations thereof.

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