Pharmaceutical packages with coatings comprising polycyanurates

Abstract

The present disclosure is directed to pharmaceutical packages which include a coating that comprises polycyanurate, and methods for the production of such. In one or more embodiments of the present disclosure, a pharmaceutical package may comprise a glass container comprising a first surface and a second surface opposite the first surface. The first surface may be an outer surface of the glass container. The pharmaceutical package may further comprise a coating positioned over at least a portion of the first surface of the glass container. The coating may comprise polycyanurate.

1 - 9 . (canceled) 
     
     
         10 . A pharmaceutical package comprising:
 a glass container comprising a first surface and a second surface opposite the first surface, wherein the first surface is an outer surface of the glass container; and   a coating positioned over at least a portion of the first surface of the glass container, the coating formed from one or more cyanate esters.   
     
     
         11 . The pharmaceutical package of  claim 10 , wherein the one or more cyanate esters are chosen from one or more bisphenol cyanate esters. 
     
     
         12 . The pharmaceutical package of  claim 11 , wherein the one or more bisphenol cyanate esters are chosen from bisphenol A cyanate ester, bisphenol E cyanate ester, C,C′-((2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)di-4,1-phenylene) ester, tetramethylbisphenol F cyanate ester, bisphenol M cyanate ester, C,C′-((2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)di-4,1-phenylene) ester, or combinations thereof. 
     
     
         13 . The pharmaceutical package of  claim 11 , wherein the coating has a thickness of 100 nm or less. 
     
     
         14 . The pharmaceutical package of  claim 11 , wherein the coating is in direct contact with at least a portion of the first surface of the glass container. 
     
     
         15 . The pharmaceutical package of  claim 11 , wherein the portion of the first surface of the glass container with the coating has a coefficient of friction of less than or equal to about 0.7. 
     
     
         16 . The pharmaceutical package of  claim 11 , wherein a light transmission through the pharmaceutical package is greater than or equal to about 55% of a light transmission through an uncoated pharmaceutical package for each wavelength from about 400 nm to about 700 nm. 
     
     
         17 . A method producing a coated pharmaceutical package, the method comprising:
 depositing a coating precursor mixture onto a first surface of an outer surface of a glass container, the coating precursor mixture comprising one or more cyanate esters; and   heating the coating precursor mixture to form a coating on the outer surface of the glass container, the coating comprising polycyanurate.   
     
     
         18 . The method of  claim 17 , wherein the one or more cyanate esters are chosen from one or more bisphenol cyanate esters. 
     
     
         19 . The pharmaceutical package of  claim 11 , wherein the one or more bisphenol cyanate esters are chosen from bisphenol A cyanate ester, bisphenol E cyanate ester, C,C′42,2,2-trifluoro-1-(trifluoromethyl)ethylidene)di-4,1-phenylene) ester, tetramethylbisphenol F cyanate ester, bisphenol M cyanate ester, C,C′-((2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)di-4,1-phenylene) ester, or combinations thereof. 
     
     
         20 . The method of  claim 18 , wherein the heating of the coating precursor mixture is at a temperature of less than 230° C.