US2024024296A1PendingUtilityA1

Combination therapy for treatment of restenosis

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Assignee: MERCATOR MEDSYSTEMS INCPriority: May 26, 2017Filed: Oct 4, 2023Published: Jan 25, 2024
Est. expiryMay 26, 2037(~10.9 yrs left)· nominal 20-yr term from priority
A61K 31/436A61P 9/14A61P 9/04A61K 9/0019A61P 9/10A61K 31/573A61K 47/10A61K 47/22A61K 47/12A61K 47/26A61K 31/337A61K 45/06A61K 9/14A61K 2300/00
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Claims

Abstract

Described herein are methods for distributing a combination of a cell division inhibitor (e.g., temsirolimus or paclitaxel) and dexamethasone to a tissue surrounding a blood vessel for treating vascular diseases. Also disclosed are injectable compositions of a cell division inhibitor (e.g., temsirolimus or paclitaxel) and dexamethasone for delivery into the tissue surrounding a blood vessel for treating vascular diseases.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating a vascular disease in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of temsirolimus or a pharmaceutically acceptable salt thereof and a therapeutically effective amount of dexamethasone or a pharmaceutically acceptable salt thereof, wherein the composition is administered by direct injection to a disease site.

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