US2024033311A1PendingUtilityA1

Composition and functional food for preventing myopia

Assignee: TSUBOTA LAB INCPriority: May 15, 2017Filed: Oct 9, 2023Published: Feb 1, 2024
Est. expiryMay 15, 2037(~10.8 yrs left)· nominal 20-yr term from priority
A61K 31/05A61K 36/16A61P 27/10A61K 9/0056A61K 31/202A23L 33/105A61P 27/02A61P 39/06A61P 43/00G01N 33/15G01N 33/50A61K 36/88A61K 31/353
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Claims

Abstract

The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of normalizing refractive changes in an eye of a subject in need thereof, the method comprising administering to the subject a composition comprising crocetin and/or a pharmaceutically acceptable salt thereof and  Ginkgo biloba  leaf extract as active ingredients. 
     
     
         2 . The method according to  claim 1 , wherein the daily intake of said active ingredients is 0.01-500 mg/day. 
     
     
         3 . The method according to  claim 1 , wherein the subject is a child, a near-industrial work, or an indoor worker. 
     
     
         4 . The method according to  claim 1 , wherein the composition is taken for at least three weeks. 
     
     
         5 . A method for preventing, treating, or inhibiting myopia progression in a subject in need thereof, the method comprising administering to the subject a composition comprising crocetin and/or a pharmaceutically acceptable salt thereof and  Ginkgo biloba  leaf extract as active ingredients. 
     
     
         6 . The method according to  claim 5 , wherein the daily intake of said active ingredients is 0.01-500 mg/day. 
     
     
         7 . The method according to  claim 5 , wherein the subject is a child, a near-industrial work, or an indoor worker. 
     
     
         8 . The method according to  claim 5 , wherein the composition is taken for at least three weeks.

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