US2024036031A1PendingUtilityA1
Microfluidic tissue biopsy and immune response drug evaluation devices and systems
Assignee: CHARLES STARK DRAPER LABORATORY INCPriority: Aug 30, 2017Filed: Oct 16, 2023Published: Feb 1, 2024
Est. expiryAug 30, 2037(~11.1 yrs left)· nominal 20-yr term from priority
Inventors:Ashley Lynne BeckwithJeffrey T. BorensteinNathan MooreDaniel DotyLuis Fernando Velásquez-García
G01N 33/5008C12M 23/12B01L 3/502761G01N 33/5082C12M 23/16B01L 2200/027B01L 2200/0668B01L 2200/0684B01L 2300/0816B01L 2300/0864B01L 2300/0877B01L 2300/0883B01L 2400/0463B01L 2400/0487B01L 2400/086
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Abstract
This disclosure describes microfluidic tissue biopsy and immune response drug evaluation devices and systems. A microfluidic device can include an inlet channel having a first end configured to receive a fluid sample optionally containing a tissue sample. The microfluidic device can also include a tissue trapping region at the second end of the inlet channel downstream from the first end. The tissue trapping region can include one or more tissue traps configured to catch a tissue sample flowing through the inlet channel such that the fluid sample contacts the tissue trap. The microfluidic device can also include one or more channels providing an outlet.
Claims
exact text as granted — not AI-modified1 . A microfluidic device comprising: a substrate defining: an inlet channel having a first end configured to receive a fluid sample optionally containing a tissue sample; a tissue trapping region at the second end of the inlet channel downstream from the first end, the tissue trapping region including one or more tissue traps configured to catch a tissue sample flowing through the inlet channel such that the fluid sample contacts the tissue trap; and one or more channels providing an outlet.
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