US2024043428A1PendingUtilityA1
Pyrrolopyrimidine compounds and their uses
Est. expiryAug 22, 2028(~2.1 yrs left)· nominal 20-yr term from priority
Inventors:Gilbert Ebai BesongChristopher Thomas BrainClinton A. BrooksMiles Stuart CongreveClaudio DagostinGuo HeYing HouSteven HowardYue LiYipin LuPaul MortensonTroy Douglas SmithMoo Je SungSteven John WoodheadWojciech WronaBharat Lagu
C07D 487/04A61P 35/00C07D 487/08A61K 31/519C07D 519/00A61P 25/28A61P 29/00A61P 35/02A61P 35/04A61P 37/00A61P 37/06A61P 43/00
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Abstract
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
Claims
exact text as granted — not AI-modified1 - 22 . (canceled)
23 . A compound 7-Cyclopentyl-2-{6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-pyridazin-3-ylamino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide of the formula
or a pharmaceutically acceptable salt thereof.Cited by (0)
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