US2024043518A1PendingUtilityA1

Heavy chain only antibodies to pdgf

Assignee: ALLERGAN INCPriority: Aug 14, 2015Filed: May 24, 2023Published: Feb 8, 2024
Est. expiryAug 14, 2035(~9 yrs left)· nominal 20-yr term from priority
C07K 16/22A61K 39/395C07K 2317/565C07K 2317/52C07K 2317/92C07K 2317/76C07K 2317/64C07K 2317/24C07K 2317/522C07K 2317/569A61K 39/3955A61P 27/02A61P 35/00A61P 9/00
83
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

Disclosed herein are monospecific HCAb antibodies with antigen-binding specificity to PDGF and bispecific antibodies with antigen-binding specificities to PDGF-2 and VEGF or to PDGF and ANG-2.

Claims

exact text as granted — not AI-modified
1 .- 40 . (canceled) 
     
     
         41 . A heavy chain only antibody (HCAb) with an antigen-binding specificity for PDGF, wherein the HCAb comprises a homodimeric variable heavy chain (VH) region with each VH region comprising: a CDR1 having the amino acid sequence of SEQ ID NO:23; a CDR2 having the amino acid sequence of SEQ ID NO:24; and a CDR3 having the amino acid sequence of SEQ ID NO:25.

Join the waitlist — get patent alerts

Track US2024043518A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.