Orthopedic attachment systems and methods thereof

Abstract

An orthopedic attachment system such as a suture anchor system. The suture anchor system may include a suture anchor having a body portion with an aperture disposed therethrough. The suture anchor system may include a composite medical suture at least partially disposed in the aperture of the suture anchor. The composite medical suture may include a first plurality of fibers comprising a bioresorbable hyaluronan-based polymer and a second plurality of fibers comprising a non-resorbable polymer. Methods of using the orthopedic attachment system and making the medical textile are also disclosed.

1 . A suture anchor system comprising:
 a rigid suture anchor having a first end, a second end, and a body portion therebetween, wherein the body portion comprises an aperture disposed through the body portion;   a composite medical suture at least partially disposed in the aperture of the rigid suture anchor comprising a first plurality of fibers comprising a bioresorbable hyaluronan-based polymer and a second plurality of fibers comprising a non-bioresorbable polymer.   
     
     
         2 . The suture anchor system of  claim 1 , wherein the rigid suture anchor is selected from the group consisting of a rigid bone anchor and a soft tissue anchor. 
     
     
         3 . (canceled) 
     
     
         4 . The suture anchor system of  claim 1 , wherein the rigid suture anchor is configured to detachably couple with a deployment tool configured to place the suture anchor system at least partially into a patient. 
     
     
         5 . The suture anchor system of  claim 1 , wherein the rigid suture anchor is biostable or bioresorbable. 
     
     
         6 . The suture anchor system of  claim 1 , wherein the first plurality of fibers comprises one or both of mono filaments and multifilaments. 
     
     
         7 . The suture anchor system of  claim 1 , where the composite medical suture is circular in cross section. 
     
     
         8 . The suture anchor system of  claim 1 , wherein the composite medical suture is a tape and has a cross section comprising at least one selected from the group consisting of rounded rectangular, marquise, oblong, and oval. 
     
     
         9 . The suture anchor system of  claim 1 , wherein the composite medical suture has a diameter of from 25 m to about 5000 m. 
     
     
         10 . The suture anchor system of  claim 1 , wherein the first plurality of fibers and the second plurality of fibers are joined together by at least one method selected from the group consisting of braided, knitted, adhered, intermeshed, weaved, interlocked, twisted, and heat set. 
     
     
         11 . The suture anchor system of  claim 1 , wherein the first plurality of fibers is prepared by at least one method selected from the group consisting of ring spinning, air-jet spinning, open-end spinning, mule spinning, wet spinning, dry spinning, electrospinning, pneumatospinning, extrusion, and pultrusion. 
     
     
         12 . The suture anchor system of  claim 1 , wherein the composite medical suture comprises from 10% to 98% of the second plurality of fibers, based on a weight of the second plurality of fibers to a total weight of the second plurality of fibers and the first plurality of fibers together. 
     
     
         13 . The suture anchor system of  claim 1 , wherein the second plurality of fibers comprise at least one material selected from the group consisting of ultra-high molecular weight polyethylene (UHMWPE), polypropylene, polyethylene terephthalate (PET), polyethylene, polytetrafluoroethylene (Teflon), Dacron, steel, polybutester, polyamide, polyester, polyurethane, nylons, silk, and cotton. 
     
     
         14 . The suture anchor system of  claim 1 , further comprising a third plurality of fibers comprising at least one bioresorbable polymer selected from the group consisting of collagen, polylactic acid (PLA), polyglycolic acid (PGA), polylactic-co-glycolic acid (PLGA), polycaprolactone (PCL), polydioxanone (PDO), polyhydroxybutyrate (PHB), polyhydroxyvalerate (PHV), Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), alginate, chitosan, chitin, polylysine, fibrin, pectin, dextran, carrageenan, chondroitin sulfate, agar, gelatin, gellan gum, silk, and butyric acid. 
     
     
         15 . The suture anchor system of  claim 1 , wherein the first plurality of fibers comprises benzyl esters of hyaluronic acid. 
     
     
         16 . The suture anchor system of  claim 1 , wherein a precursor of the first plurality of fibers and a first active agent are homogeneously mixed and co-extruded to embed the first active agent within the first plurality of fibers. 
     
     
         17 . The suture anchor system of  claim 16 , wherein the first active agent is selected from the group consisting of an antimicrobial agent, an analgesic, and a vasoconstrictive agent. 
     
     
         18 . The suture anchor system of  claim 16 , wherein one or both of the second plurality of fibers and the first plurality of fibers are wetted with the first active agent. 
     
     
         19 . The suture anchor system of  claim 16 , wherein the precursor and the first active agent are co-extruded via at least one method selected from the group consisting of solvent exchange extrusion, precipitation extrusion, phase exchange extrusion, and phase change extrusion. 
     
     
         20 . An orthopedic attachment system comprising:
 a flexible tubular connector having a lumen disposed at least partially through a longitudinal axis;   a first plurality of bioresorbable hyaluronan-based fibers at least partially disposed within the lumen of the flexible tubular connector;   a second plurality of non-resorbable fibers at least partially disposed within the lumen of the flexible tubular connector and configured to be joined with the first plurality of bioresorbable hyaluronan-based fibers; and   an orthopedic attachment device configured to couple with the flexible tubular connector.