US2025151757A1PendingUtilityA1

Probiotic for poultry or cud-chewing animals

Assignee: LESAFFRE & CIEPriority: May 15, 2018Filed: Dec 30, 2024Published: May 15, 2025
Est. expiryMay 15, 2038(~11.8 yrs left)· nominal 20-yr term from priority
C12R 2001/865C12N 1/185A23K 50/75A23K 50/10A23V 2002/00A23K 10/18A61P 39/02A61P 1/00A61K 36/064C12N 1/36C12N 1/165A23L 33/14C12N 1/16
73
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

An active yeast adapted to weak organic acids and to the use thereof for poultry or cud-chewing animals. Also, a probiotic for poultry or cud-chewing animals, including an active yeast adapted to weak organic acids. Further, the use of such a yeast for improving the zootechnical performances of poultry and to the use thereof in a probiotic and/or food for poultry. Furthermore, the use of such a yeast for improving the physico-chemical and fermentative parameters of the rumen of cud-chewing animals, and to the use thereof in a probiotic and/or food for cud-chewing animals. In addition, a yeast for use in the prevention and/or the treatment of digestive disorders in cud-chewing animals and particularly in the prevention of acidosis in cud-chewing animals.

Claims

exact text as granted — not AI-modified
1 . A method for preventing and/or treating acidosis in a ruminant animal, comprising:
 administering to a ruminant animal in need thereof an effective amount of a  Saccharomyces cerevisiae  active yeast adapted to a weak organic acid selected from the group consisting of propionic acid, benzoic acid, and salts thereof,   wherein:   said adapted  Saccharomyces cerevisiae  active yeast is obtained by adapting a  Saccharomyces cerevisiae  active yeast derived from a strain chosen from strains deposited at the CNCM under number I-5129 on Aug. 31, 2016 and number I-5223 on Aug. 30, 2017, to the presence of a weak organic acid and carried out during the final hours of a final multiplication stage by addition of 0.1 g to 10 g of weak organic acid and/or salts thereof, per liter of culture medium, so as to obtain between 1500 and 3000 ppm of weak organic acid by weight in the culture medium;   a ratio of a volume of CO 2  given off for 2 hours of culture from said adapted  Saccharomyces cerevisiae  active yeast derived from the strain chosen from I-5129 and I-5223 to a volume of CO 2  given off for 2 hours of culture from a non-adapted  Saccharomyces cerevisiae  active yeast derived from the strain chosen from I-5129 and I-5223 is greater than or equal to 1; and   said adapted  Saccharomyces cerevisiae  active yeast has an increased tolerance to a weak organic acid by virtue of a first exposure to said weak organic acid during the final multiplication stage such that said adapted  Saccharomyces cerevisiae  active yeast has a growth and a fermentative capacity of that are not inhibited when said adapted  Saccharomyces cerevisiae  active yeast is in the presence of said weak organic acid for at least a second exposure.   
     
     
         2 . The method as claimed in  claim 1 , wherein the effective amount of the adapted  Saccharomyces cerevisiae  active yeast maintains and/or reestablishes a pH in the rumen of the ruminant animal to a value greater or equal to 5.8. 
     
     
         3 . The method as claimed in  claim 1 , wherein the effective amount of the adapted  Saccharomyces cerevisiae  active yeast maintains and/or reestablishes a redox potential in the rumen of the ruminant animal to a value in a range from −200 mV to −150 mV. 
     
     
         4 . The method as claimed in  claim 1 , wherein the effective amount of the adapted  Saccharomyces cerevisiae  active yeast increases volatile fatty acid concentration in the rumen of the ruminant animal. 
     
     
         5 . The method as claimed in  claim 1 , wherein the effective amount administered to the ruminant animal is 0.5 g to 50 g of the adapted  Saccharomyces cerevisiae  active yeast per day. 
     
     
         6 . The method as claimed in  claim 1 , wherein the adapted  Saccharomyces cerevisiae  active yeast is in dry form. 
     
     
         7 . The method as claimed in  claim 1 , wherein the adapted  Saccharomyces cerevisiae  active yeast is in the form of granules, microspherules, meal, or in a water-dispersible form. 
     
     
         8 . The method as claimed in  claim 1 , wherein the ruminant is of the bovid or camelid family. 
     
     
         9 . The method as claimed in  claim 8 , wherein the ruminant is a bovid selected from bovines and caprinae. 
     
     
         10 . The method as claimed in  claim 8 , wherein the ruminant is a camelid selected from the group consisting of dromedary, camel, and llama.

Join the waitlist — get patent alerts

Track US2025151757A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.