US2025213462A1PendingUtilityA1

Novel photonic crystal proteins from atrina sp. byssus and uses thereof

Assignee: POSTECH RES & BUSINESS DEV FOUNDPriority: Dec 27, 2023Filed: Dec 27, 2024Published: Jul 3, 2025
Est. expiryDec 27, 2043(~17.4 yrs left)· nominal 20-yr term from priority
A61Q 19/00A61Q 19/007A61K 8/987A61Q 19/08A61K 8/64A61K 8/027
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Claims

Abstract

The present invention relates to a novel photonic crystal protein derived from Atrina sp. byssus and its use. According to the present disclosure, seasilk, which is processed to have a specific color using the byssus of Atrina sp., has a less impact on the marine ecosystem in terms of utilization of waste resources and a high economic value and thus can be actively used as eco-friendly and functional fibers and cosmetic materials.

Claims

exact text as granted — not AI-modified
1 . A method for producing a golden seasilk fiber derived from  Atrina  sp. byssus, comprising treating a seasilk fiber derived from  Atrina  sp. byssus, which is isolated from  Atrina  sp. byssus, with an acid solution. 
     
     
         2 . The method of  claim 1 , wherein the seasilk fiber derived from  Atrina  sp. byssus comprises a photonic crystal Photonin-1 protein derived from  Atrina  sp. byssus, consisting of an amino acid sequence as set forth in SEQ ID NO: 1, and a photonic crystal Photonin-2 protein derived from  Atrina  sp. byssus, consisting of an amino acid sequence as set forth in SEQ ID NO: 2. 
     
     
         3 . The method of  claim 1 , wherein the seasilk fiber derived from  Atrina  sp. byssus becomes a golden seasilk fiber having a golden structural color that does not fade due to a change in longitudinal repeating structure induced by acid treatment. 
     
     
         4 . The method of  claim 1 , wherein the golden seasilk fiber derived from  Atrina  sp. byssus has a hierarchical structure stabilized by sugar-lectin interactions and has a structural color. 
     
     
         5 . The method of  claim 1 , wherein the acidic solution is at least one selected from the group consisting of sodium citrate, acetic acid, boric acid, sorbic acid, citric acid, sodium phosphate, dibasic sodium phosphate, monobasic sodium phosphate, potassium dihydrogen phosphate, hydrochloric acid, sodium hydroxide, sodium thiosulfate, sodium sulfite, sodium sulphate, tris(hydroxymethyl)aminomethane, tris(hydroxymethyl)aminomethane hydrochloride, sodium hydrogen carbonate, sodium borate, sodium acetate, sodium bisulphate and sodium benzoate. 
     
     
         6 . The method of  claim 1 , wherein the acidic solution is at least one selected from the group consisting of lemon juice, citron juice, sugar citron juice, orange juice,  magnolia  berry juice, bokbunja juice, wolfberry juice, cornelian cherry juice, plum juice, and vinegar. 
     
     
         7 . The method of  claim 1 , wherein the seasilk fiber derived from  Atrina  sp. byssus and the acidic solution are treated at a ratio of 1:1000 to 1000:1 (w/w). 
     
     
         8 . A composition for producing a golden seasilk fiber comprising the golden seasilk fiber derived from  Atrina  sp. byssus, produced according to the producing method of  claim 1 . 
     
     
         9 . A functional cosmetic composition for improving skin, comprising a seasilk fiber derived from  Atrina  sp. byssus; or a golden seasilk fiber derived from  Atrina  sp. byssus as an active ingredient. 
     
     
         10 . The composition of  claim 9 , wherein the seasilk fiber derived from  Atrina  sp. byssus and the golden seasilk fiber derived from  Atrina  sp. byssus comprise a photonic crystal Photonin-1 protein derived from  Atrina  sp. byssus, consisting of an amino acid sequence as set forth in SEQ ID NO: 1 and a photonic crystal Photonin-2 protein derived from  Atrina  sp. byssus, consisting of an amino acid sequence as set forth in SEQ ID NO: 2. 
     
     
         11 . The composition of  claim 9 , wherein the seasilk fiber derived from  Atrina  sp. byssus becomes a golden seasilk fiber having a golden structural color that does not fade due to a change in longitudinal repeating structure induced by acid treatment. 
     
     
         12 . The composition of  claim 9 , wherein the golden seasilk fiber derived from  Atrina  sp. byssus has a hierarchical structure stabilized by sugar-lectin interactions and has a structural color. 
     
     
         13 . The composition of  claim 9 , wherein the skin improvement is selected from the group consisting of improved skin moisturizing, improved skin wrinkles, improved skin thickness, improved skin elasticity, improved skin barrier, improved skin texture, and improved pigmentation. 
     
     
         14 . The composition of  claim 9 , wherein the composition has growth promoting activity of human skin fibroblasts. 
     
     
         15 . The composition of  claim 9 , wherein the formulation of the cosmetic composition is at least one selected from the group consisting of a toner, a nourishing toner, a massage cream, a nourishing cream, a pack, a gel, a skin adhesive type cosmetic, a lipstick, a makeup base, a foundation, a shampoo, a rinse, a body cleanser, a soap, a lotion, an ointment, a gel, a cream, a patch, and a spray.

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