Flexible neural electrode composite structure and manufacturing and implantation method therefor

Abstract

A flexible neural electrode composite structure and a manufacturing and an implantation method therefor are provided. The flexible neural electrode composite structure includes: a plurality of flexible neural electrodes, each flexible neural electrode including an implant portion and an auxiliary structure provided at the implant portion; an auxiliary implantation assembly, which includes a plurality of auxiliary implantation needles corresponding to the plurality of flexible neural electrodes on a one-to-one basis, wherein each auxiliary implantation needle includes an auxiliary implantation end located close to one end of a corresponding flexible neural electrode, and the auxiliary implantation end is configured to be assembled with the auxiliary structure corresponding thereto; and a fixture, which is configured to fix the assembled auxiliary implantation ends and auxiliary structures.

1 . A flexible neural electrode composite structure, comprising:
 a plurality of flexible neural electrodes, each of the plurality of flexible neural electrodes comprising an implant part and an auxiliary structure provided on the implant part;   an auxiliary implantation assembly comprising a plurality of auxiliary implantation needles in one-to-one correspondence with the plurality of flexible neural electrodes, each of the plurality of auxiliary implantation needles comprising an auxiliary implantation end located close to one end of a corresponding flexible neural electrode, and the auxiliary implantation end being configured to be assembled with the auxiliary structure; and   a fixture configured to fix the auxiliary implantation end and the auxiliary structure which have been assembled.   
     
     
         2 . The flexible neural electrode composite structure according to  claim 1 , wherein an extension direction of the plurality of auxiliary implantation needles is not parallel to an extension direction of a plurality of implant parts of the plurality of flexible neural electrodes. 
     
     
         3 . The flexible neural electrode composite structure according to  claim 2 , wherein each of the implant parts has a linear structure, and the extension direction of the plurality of auxiliary implantation needles is not parallel to an extension direction of a plurality of linear structures. 
     
     
         4 . The flexible neural electrode composite structure according to  claim 2 , wherein each of the implant parts has a stretchable spiral structure, and the extension direction of the plurality of auxiliary implantation needles is not parallel to a plane where a plurality of spiral structures is located. 
     
     
         5 . The flexible neural electrode composite structure according to  claim 4 , wherein the auxiliary structure is located at an end of the stretchable spiral structure. 
     
     
         6 . The flexible neural electrode composite structure according to  claim 2 , wherein the plurality of flexible neural electrodes comprise a plurality of implant parts, and a part of the plurality of implant parts have a linear structure, and the other part of the plurality of implant parts have a stretchable spiral structure. 
     
     
         7 . (canceled) 
     
     
         8 . The flexible neural electrode composite structure according to  claim 1 , wherein the auxiliary implantation end and the auxiliary structure are configured to be assembled with each other by way of plugging-in. 
     
     
         9 . The flexible neural electrode composite structure according to  claim 8 , wherein the auxiliary implantation end is configured to be partially or completely inserted into the auxiliary structure. 
     
     
         10 . The flexible neural electrode composite structure according to  claim 9 , wherein the auxiliary structure is a through hole, a groove or a protrusion located on the implant part. 
     
     
         11 - 12 . (canceled) 
     
     
         13 . The flexible neural electrode composite structure according to  claim 1 , wherein the auxiliary implantation assembly further comprises:
 an auxiliary fixing member located at one side of the plurality of auxiliary implantation needles away from the plurality of flexible neural electrodes and configured to fix the plurality of auxiliary implantation needles.   
     
     
         14 . The flexible neural electrode composite structure according to  claim 13 , wherein the auxiliary fixing member comprises an auxiliary fixing plate, and a plane where the auxiliary fixing plate is located is perpendicular to an extension direction of the plurality of auxiliary implantation needles. 
     
     
         15 . (canceled) 
     
     
         16 . The flexible neural electrode composite structure according to  claim 14 , wherein the auxiliary fixing plate and the plurality of auxiliary implantation needles are configured to be detachably or fixedly connected. 
     
     
         17 . The flexible neural electrode composite structure according to  claim 16 , wherein the auxiliary fixing plate is provided with a plurality of openings, and the plurality of auxiliary implantation needles comprise fixing ends away from the auxiliary implantation ends along the extension direction of the plurality of auxiliary implantation needles, and the fixing ends are configured to pass through the plurality of openings to be connected with the auxiliary fixing plate. 
     
     
         18 . (canceled) 
     
     
         19 . The flexible neural electrode composite structure according to  claim 1 , wherein at least part of the fixture is located between the auxiliary implantation end and the auxiliary structure to maintain a relative position between the auxiliary implantation end and the auxiliary structure. 
     
     
         20 . The flexible neural electrode composite structure according to  claim 19 , wherein the fixture comprises one or more selected from a group consisting of a photo-meltable material, a thermal-meltable material, a liquid-swellable material and a liquid-dissolvable material. 
     
     
         21 - 23 . (canceled) 
     
     
         24 . A manufacturing method of a flexible neural electrode composite structure, comprising:
 providing a plurality of flexible neural electrodes, wherein each of the plurality of flexible neural electrodes comprises an implant part and an auxiliary structure formed on the implant part;   forming an auxiliary implantation assembly, wherein the auxiliary implantation assembly comprises a plurality of auxiliary implantation needles, and each of the plurality of auxiliary implantation needles comprises an auxiliary implantation end located at one side of the auxiliary implantation needle close to the plurality of flexible neural electrodes;   assembling the auxiliary implantation end with the auxiliary structure; and   fixing the auxiliary implantation end and the auxiliary structure which have been assembled.   
     
     
         25 - 27 . (canceled) 
     
     
         28 . An implantation method of flexible neural electrodes adopting the flexible neural electrode composite structure according to  claim 1 , the implantation method comprising:
 moving the flexible neural electrode composite structure to drive the implant parts of the plurality of flexible neural electrodes to move to a surface of a target tissue;   melting or dissolving the fixture, so that the auxiliary implantation end and the auxiliary structure are in a separable state;   moving the auxiliary implantation assembly towards the target tissue to drive a plurality of implant parts of the plurality of flexible neural electrodes to move to the target tissue; and   removing the auxiliary implantation assembly, and leaving at least part of the plurality of flexible neural electrodes at the target tissue.   
     
     
         29 . The implantation method of flexible neural electrodes according to  claim 28 , wherein when moving the auxiliary implantation assembly towards the target tissue, the plurality of implant parts of the plurality of flexible neural electrodes are moved to the target tissue at the same time. 
     
     
         30 . The implantation method of flexible neural electrodes according to  claim 28 , wherein the plurality of flexible neural electrodes comprise a plurality of implant parts, each of the plurality of implant parts has a stretchable spiral structure, and the auxiliary structure is located on the stretchable spiral structure, and
 the moving the auxiliary implantation assembly towards the target tissue to drive a plurality of implant parts of the plurality of flexible neural electrodes to move to the target tissue comprises:   moving the auxiliary structure by utilizing the auxiliary implantation end so as to unfold the stretchable spiral structure.   
     
     
         31 . The implantation method of flexible neural electrodes according to  claim 28 , wherein the plurality of flexible neural electrodes comprise a plurality of implant parts, each of the plurality of implant parts has a linear structure, and the auxiliary structure is located on the linear structure,
 the moving the auxiliary implantation assembly towards the target tissue to drive a plurality of implant parts of the plurality of flexible neural electrodes to move to the target tissue comprises:   moving the auxiliary structure by utilizing the auxiliary implantation end to drive the linear structure to move to the target tissue.   
     
     
         32 - 38 . (canceled)