US3944673AExpiredUtilityPatentIndex 92
Hexahydro-dibenzo[b,d]pyran-9-ones as analgesic drugs
Est. expiryNov 5, 1993(expired)· nominal 20-yr term from priority
Inventors:ARCHER ROBERT A
C07C 49/747C07D 311/80
92
PatentIndex Score
39
Cited by
2
References
7
Claims
Abstract
Use of 1-hydroxy-3-alkyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones as an analgesic drug and pharmaceutical compositions containing same.
Claims
exact text as granted — not AI-modifiedI claim:
1. A process for providing analgesia to mammals suffering from pain which comprises administering to a mammal in need of analgesia an analgetic dose of a compound represented by the formula ##SPC7## wherein R' is either C 7 -C 10 normal alkyl or is the group ##EQU3## wherein R" is C 2 -C 7 alkyl and R v is H or methyl, wherein both R groups are identical and are H or methyl and wherein R'" is H or C 1 -C 4 alkanoyl, in an amount effective to provide analgesia.
2. A process according to claim 1 in which a dose of from 0.1 to 100 mgs per day of the drug is administered.
3. A process according to claim 1 in which a dose of from 1 to 20 mgs. per day of the drug is administered.
4. A process according to claim 1 in which the drug is administered by the oral route.
5. A process according to claim 1 in which dl-trans-1-hydroxy-3-(1',1'-dimethylheptyl)-6,6a,7,8,10,10a-hexahydro-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one is administered.
6. A process according to claim 1 in which dl-trans-1-hydroxy-3-(1',2'-dimethylheptyl)-6,6a,7,8,10,10a-hexahydro-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one is administered.
7. A process according to claim 1 in which dl-trans-1-hydroxy-3-(1'-methylheptyl)-6,6a,7,8,10,10a-hexahydro-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one is administered.Cited by (0)
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