US3953456AExpiredUtility

Carbostyril derivatives and process for preparing the same

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Assignee: OTSUKA PHARMA CO LTDPriority: Dec 14, 1972Filed: Dec 14, 1973Granted: Apr 27, 1976
Est. expiryDec 14, 1992(expired)· nominal 20-yr term from priority
A61P 9/08C07D 215/26A61P 9/10A61P 9/06C07D 215/227
51
PatentIndex Score
11
Cited by
4
References
6
Claims

Abstract

2-Hydroxy-3-alkylaminopropoxycarbostyrils represented by the formula (I) ##SPC1## wherein R represents a straight or branched chain alkyl group having 1 to 4 carbon atoms useful as β-adrenergic blocking agents and a process for preparing the same are disclosed.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A 5- or 8- (2-Hydroxy-3-alkylamino)propoxycarbostyril compound represented by the formula (I): ##SPC4## wherein R represents a straight or branched alkyl group having 1 to 4 carbon atoms, and the pharmaceutically acceptable acid addition salts thereof.   
     
     
       2. 5-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1. 
     
     
       3. 5-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1. 
     
     
       4. 8-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1. 
     
     
       5. 8-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1. 
     
     
       6. 8-(2-Hydroxy-3-sec-butylamino)propoxycarbostyril according to claim 1.

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