US4016223AExpiredUtility

Prostaglandin dehydrogenase inhibiting agents

75
Assignee: NELSON RES & DEVPriority: Aug 7, 1975Filed: Aug 7, 1975Granted: Apr 5, 1977
Est. expiryAug 7, 1995(expired)· nominal 20-yr term from priority
C07F 9/12C07C 205/45C07C 49/835C07C 45/75C07C 45/74
75
PatentIndex Score
10
Cited by
1
References
2
Claims

Abstract

Novel prostaglandin dehydrogenase inhibiting agents having the structural formula <IMAGE> <IMAGE> M is H or a pharmaceutically acceptable salt, X is hydrogen, dialkylaminomethyl, lower alkyl, lower alkoxy, aryl, substituted aryl, halogen, cyano, nitro, trihaloalkyl, -NR1R2 or -NHCOR1 where R1 and R2 are hydrogen, lower alkyl or NH2 and n is 0-5.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. Compounds having the structural formula ##STR37## wherein M is H or a pharmaceutically acceptable salt; and X is selected from the group consisting of H, halogen, NO 2 , lower alkyl and amino, and n is 0-5. 
     
     
       2. A compound having the structural formula ##STR38## wherein M is H or a pharmaceutically acceptable salt.

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