3-[2-(Dialkylamino)ethyl]-2-(benzyl)indoles

Abstract

3-[2-(Dialkylamino)ethyl]-2-(benzyl)indoles having in free base form the formula ##STR1## where R 1 and R 2 are lower alkyl groups and R 3 is a phenyl, carboalkoxymethyl, lower alkyl or hydroxyethyl group. The compounds of the invention exhibit anti-aggression and anti-secretory properties and are indicated in the management of aggression and gastric hypersecretion.

We claim: 
     
       1. A compound of the formula ##STR4## where R 1  and R 2  are alkyl groups having 1 to 4 carbon atoms and R 3  is phenyl, carboloweralkoxymethyl, lower alkyl or hydroxyethyl and the corresponding pharmaceutically acceptable acid addition salts. 
     
     
       2. A compound according to claim 1 which is 3-[2-(dimethylamino)ethyl]-2-[α-(phenylthio)benzyl]indole. 
     
     
       3. A compound according to claim 1 which is 3-[2-(dimethylamino)ethyl]-2-[α-(ethylthio)benzyl]indole. 
     
     
       4. A compound according to claim 1 which is 2-[({3[2-(dimethylamino)ethyl]-1H-indol-2-yl}phenylmethyl)thio]ethanol. 
     
     
       5. A compound according to claim 1 which is methyl[({3-[2-(dimethylamino)ethyl]-1H-indol-2-yl}phenylmethyl)-thio]acetate.