Method of treatment

Abstract

This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of α-phenyl-N-phenylnitrone and derivatives thereof.

We claim: 
     
       1. A method of treating inflammation in warm-blooded animals comprising the topical administration to said animal of an effective amount of a pharmaceutically-active compound of the formula: ##STR6## where: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9  and R 10  may be the same or different and are: hydrogen,   alkyl,   cyano,   nitro,   amino,   haloloweralkoxy,   haloloweralkyl,   halo,   loweralkoxy and   hydroxy.   
     
     
       2. The method of topically treating inflammation according to claim 1 where the compound administered is α-phenyl-N-p-chlorophenylnitrone. 
     
     
       3. The method of topically treating inflammation according to claim 1 where the compound administered is α-4-biphenyl-N-4-chlorophenylnitrone. 
     
     
       4. The method of topically treating inflammation according to claim 1 where the compound administered is α-2-chlorophenyl-N-3-chloro-2-methylphenylnitrone.