Novel analogues of prostanoic acids not occurring in nature

Abstract

The present invention relates to novel not naturally occurring analogues of prostanoic acids of the formula ##STR1## as well as a process for their preparation. The compounds of the invention have valuable pharmacological properties similar to those of the natural prostaglandins and therefore can be used as medicaments.

We claim: 
     
       1. A compound of the formula ##STR24## physiologically tolerated salts thereof with organic and inorganic bases, and esters thereof with aliphatic, cycloaliphatic, or araliphatic alcohols of 1 to 8 carbon atoms, wherein R 1  and R 2 , taken alone, are different and are each hydrogen or hydroxy;   R 1  and R 2 , taken together, are oxygen; and   R 3  is straight chain or branched alkyl having 1 to 10 carbon atoms substituted by 0-aryl or 0-benzyl, which themselves may be substituted by one or several halogen atoms, by trifluoromethyl, by alkyl having 1 to 3 carbon atoms, by phenoxy, or by phenoxy substituted by one or several halogen atoms.   
     
     
       2. A compound as in claim 1 wherein R 1  and R 2  together are oxygen.