US4189438AExpiredUtility

Physiologically active substance esterastin

Assignee: MICROBIAL CHEM RES FOUNDPriority: Feb 8, 1977Filed: Jan 30, 1978Granted: Feb 19, 1980

Est. expiryFeb 8, 1997(expired)· nominal 20-yr term from priority

Inventors:Hamao Umezawa Takaaki Aoyagi Tomio Takeuchi Masa Hamada Masaaki Ishizuka

A61P 37/06C07D 305/12Y10S435/899C12P 17/02

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Abstract

A new physiologically active substance named esterastin is now provided, which inhibits the activity of esterase and is useful as an immunosuppressive drug. Esterastin is produced by cultivating a microorganism Streptomyces MD4-C1 identified as FERM-P 3723 or ATCC. 31336 in a culture medium under aerobic conditions and recovering it from the resulting culture. Esterastin is the compound having the formula ##STR1##

Claims

exact text as granted — not AI-modified

We claim: 
     
       1. The compound having the formula ##STR4##

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