Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines

Abstract

Compounds having the formula ##STR1## wherein R is hydrogen or alkyl, n is 0 or 1 and m is 1 or 2 have hypotensive activity. Those compounds of the above formula wherein n is 1 are useful intermediates for the preparation of other hypotensive agents having the formula ##STR2##

What is claimed is: 
     
       1. A compound having the formula ##STR12## wherein R is hydrogen or alkyl of 1 to 7 carbon atoms; m is 1 or 2; and n is 0 or 1. 
     
     
       2. A compound in accordance with claim 1 wherein m is 1 and n is 1. 
     
     
       3. A compound in accordance with claim 1 wherein R is hydrogen. 
     
     
       4. A compound in accordance with claim 1 wherein R is alkyl of 1 to 7 carbon atoms. 
     
     
       5. A compound in accordance with claim 4 wherein R is methyl. 
     
     
       6. The compound in accordance with claim 1, (4S,9aS)-hexahydro-4-methyl-1H,5H-pyrrolo-[2,1-c][1,4]-thiazepine-1,5-dione.