Basic thio-indazoles

Abstract

Compound belonging to the class of 2-benzyl-3-(3-dimethylaminopropylthio)-2H-indazole, its sulfoxide and its sulfone and their pharmacologically acceptable salts, and process for obtaining such compounds having an antiinflammatory action in the common pathological conditions.

What is claimed is: 
     
       1. A compound for use in treatment of inflammatory conditions selected from the group consisting of 2-benzyl-3-(3-dimethylaminopropylthio)-2H-indazole (I), its sulfoxide (II) and its sulfone (III) and their pharmaceutically acceptable acid addition salts: ##STR8## 
     
     
       2. The compound of claim 1, which is 2-benzyl-3-(3-dimethylaminopropylthio)-2H-indazole (I) or its pharmaceutically acceptable acid addition salts. 
     
     
       3. The compound of claim 1, which is the sulfoxide of the 2-benzyl-3-(3-dimethylaminopropyl-thio)-2H-indazole (II) or its pharmaceutically acceptable acid addition salts. 
     
     
       4. The sulfone of the 2-benzyl-3-(3-dimethylamino-propylthio)-2H-indazole (III) or its pharmaceutically acceptable acid addition salts. 
     
     
       5. A method for treating the common pathological conditions of the inflammatory type which consists in the administration of an anti-inflammatory amount of one or more of the compounds selected from the group consisting of formulae (I), (II), (III) in accordance with claim 1 and their pharmaceutically acceptable acid addition salts. 
     
     
       6. A method for treating the common pathological conditions of the inflammatory type according to claim 5 in which said administration takes place by the systemic route. 
     
     
       7. A method for treating the common pathological conditions of the inflammatory type according to claim 5 in which said administration takes place by the topical route. 
     
     
       8. A pharmaceutical composition for use in the treatment of inflammatory conditions, which comprises as a therapeutically active component an anti-inflammatory amount of at least one of the 2-benzyl-3-substituted-2H-indazole compounds and their pharmaceutically acceptable acid addition salts as claimed in claim 1.