Process for the preparation of solid drug formulations

Abstract

In order to allow for the greatest possible range of variation in the rate of liberation of active agents within an organism and to allow for the use of a wide variety of active agents in solid drug formulations, cellulose graft copolymers are employed as adjuvant. The excellent flow properties and compacting behavior of these cellulose graft copolymers allow for formulation without the need for additional process steps, while variations in the type and proportion of the grafted components allows for the synthesis of adjuvants ideally suited for a specific intended use.

I claim: 
     
       1. In a process for preparing solid drug formulations, including dosage unit amounts of an active agent and adjuvant, the improvement comprising using a cellulose graft copolymer as 30-100% of said adjuvant. 
     
     
       2. A process as defined in claim 1, wherein said active agent or agents is mixed with said cellulose graft copolymer. 
     
     
       3. A process as defined in claim 1, wherein said active agent is sprayed onto said cellulose graft copolymer. 
     
     
       4. A process as defined in claim 1, wherein said cellulose graft copolymer is used in a mixture with cellulose powder. 
     
     
       5. A process as defined in claim 1, wherein a mixture of cellulose graft copolymers is used.