Aminobenzlpropranolol and pharmaceutical preparation thereof

Abstract

1-(p-Amino-α,α-dimethylphenethylamino)-3-(1-naphthoxy)-2-propanol, 1-(p-hydroxy-α,α-dimethylphenethylamino)-3-(1-naphthoxy)-2-propanol, 1-(p-methyl-α,α-dimethylphenethylamino)-3-(1-naphthoxy)-2-propanol, 1-(p-methoxy-α,α-dimethylphenethylamino)-3-(1-naphthoxy)-2-propanol and the pharmaceutically acceptable acid addition salts thereof are effective, long lasting β-adrenergic blocking agents and areas of indication are hypertension, angina pectoris, cardiac arrythmia, and the like.

What is claimed as new and desired to be secured by Letters Patent of the United States is: 
     
       1. 1-(p-Amino -α,α-dimethylphenethylamino)-3-(1-naphthoxy)-2-propanol and the pharmaceutically acceptable acid addition salts thereof. 
     
     
       2. A method of inducing β-adrenergic receptor blocking activity in a host subject, comprising: administering to said host subject a physiologically effective amount of the compound of claim 1. 
     
     
       3. A therapeutic composition possessing β-adrenergic receptor blocking activity, comprising: a physiologically effective amount of the compound of claim 1 with a pharmaceutically acceptable carrier.