Antimicrobial bis-imidazolo-pyridine compound

Abstract

Antimicrobial compounds of the formulae: ##STR1## wherein R and R 1 =H, lower alkyl, halogen, methoxy, hydroxy, nitro, carboxy, aryl (preferably phenyl) substituted aryl (preferably substituted by lower alkyl) and sulfamyl, R 2 =hydrogen, lower alkyl, aryl (preferably phenyl) and substituted aryl (preferably substituted by lower alkyl) and wherein n is an integer from 2-20, are provided. Also provided are the method of producing such compounds.

What is claimed is: 
     
       1. A compound of the formula: ##STR5## wherein R and R 1  =H, lower alkyl, halogen, methoxy, hydroxy, nitro, carboxy, phenyl, phenyl substituted by lower alkyl or sufamyl, where R 2  =H, lower alkyl, phenyl or phenyl substituted by lower alkyl, where n is an integer from 2-20, and where x=carbon when y=nitrogen and x=nitrogen when y=carbon. 
     
     
       2. A compound of claim 1 and being selected from the group consisting of N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,5-diazahexane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,6-diazaheptane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,7-diazaoctane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,8-diazanonane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,9-diazadecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,10 diazzundecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,11-diazadodecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,12-diazatridecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-b) pyridine]-2,13-diazatetradecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,5-diazahexane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,6-diazaheptane diimidamide,   N'-N"-bis-[2,imidazolo-(4,5-c) pyridine]-2,7-diazaoctane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,8-diazanonane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,9-diazadecane diimidamide,   N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,10-diazaundecane diimidamide,   N'-N"-bis[2-imidazolo-(4,5-c) pyridine]-2,11-diazadodecane diimidamide,   N'-N"-bis'-[2-imidazolo-(4,5-c) pyridine]-2,12-diazatridecane diimidamide, and     N'-N"-bis-[2-imidazolo-(4,5-c) pyridine]-2,13-diazatetradecane diimidamide.