Intermediates for the preparation of 5-substituted oxazolidine-2,4-diones

Abstract

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

I claim: 
     
       1. A compound of the formula ##STR16## wherein Y is hydrogen or (C 1  -C 3 )alkoxy, Y' is hydrogen or (C 1  -C 3 )alkyl, and   Y" is hydrogen or halo.   
     
     
       2. The compound of claim 1 wherein Y is methoxy and Y' and Y" are each hydrogen. 
     
     
       3. The compound of claim 1 wherein Y is methoxy, Y' is hydrogen and Y" is chloro. 
     
     
       4. A compound of the formula ##STR17## wherein Y is hydrogen or (C 1  -C 3 )alkoxy, Y' is hydrogen or (C 1  -C 3 )alkyl,   Y" is hydrogen or halo, and   R a  and R b  are each independently (C 1  -C 3 )alkyl.   
     
     
       5. The compound of claim 4 wherein Y is methoxy, Y' and Y" are each hydrogen, and R a  and R b  are each methyl. 
     
     
       6. The compound of claim 4 wherein Y is methoxy, Y' is hydrogen, Y" is chloro, and R a  and R b  are each methyl. 
     
     
       7. The compound of claim 4 wherein Y is ethoxy, and Y' and Y" are each hydrogen.