Dressings, granules, and their use in treating wounds

Abstract

This invention is directed to an occlusive dressing useful for treating skin lesions and a granular material capable of interacting with wound exudate. Wounds emitting a large amount of fluid can be treated by first packing with the granular material and then covering the wound with the occlusive dressing.

What is claimed is: 
     
       1. An occlusive multi-layered wound dressing consisting essentiallly of an adhesive layer which in use contacts the wound and the surrounding normal skin, an intermediate layer of semi-open cell polymeric foam bonded to the upper surface of said adhesive layer, and an outer moisture impervious polymeric film coated or laminated to the upper surface of said foam layer, wherein said wound and skin contacting adhesive layer consists of from about 35% to about 50% by weight of low molecular weight polyisobutylenes and from about 45% to about 65% by weight of one or more water dispensible hydrocolloids selected from the group consisting of sodium carboxymethylcellulose, calcium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, collagen, and gum karaya. 
     
     
       2. The dressing of Claim 1 wherein said wound and skin contacting adhesive layer is a homogeneous blend of about 40% by weight of low molecular weight polyisobutylene, about 20% by weight of sodium carboxymethylcellulose, about 20% by weight of pectin, and about 20% by weight of gelatin. 
     
     
       3. The dressing of Claim 2 wherein said semi open-cell polymeric foam is polyurethane foam and said water impervious polymeric film is polyurethane. 
     
     
       4. The dressing of Claim 3 wherein said wound and skin contacting adhesive layer is from about 0.02 to about 0.1 inches in thickness, said polyurethane foam layer is about 0.03 to about 0.1 inches in thickness, and said water impervious polyurethane layer is about 0.001 to about 0.003 inches in thickness. 
     
     
       5. An occlusive multi-layered wound dressing consisting essentially of an adhesive layer which in use contacts the wound and the surrounding normal skin, said adhesive layer being from about 0.02 to about 0.1 inches in thickness, an intermediate layer of semi-open cell polyurethane foam bonded to the upper surface of said adhesive layer, said foam layer being from about 0.03 to about 0.1 inches in thickness, and an outer moisture impervious polyurethane film coated or laminated to the upper surface of said foam layer, said film being from about 0.001 to about 0.003 inches in thickness, wherein said wound and skin contacting adhesive layer is a homogeneous blend of about 40% by weight of low molecular weight polyisobutylene, about 20% by weight of sodium carboxymethylcellulose, about 20% by weight of pectin, and about 20% by weight of gelatin. 
     
     
       6. An occlusive multi-layered wound dressing consisting essentially of a first adhesive layer which in use contacts the wound and the surrounding normal skin, a second adhesive layer bonded to the top surface of said first adhesive layer, an intermediate layer of semi-open cell polymeric foam bonded to the upper surface of said second adhesive layer, and an outer moisture impervious polymeric film coated or laminated to the upper surface of said foam layer, wherein said first adhesive layer consists of from about 35% to about 50% by weight of low molecular weight polyisobutylene and from about 45% to about 65% by weight of one or more water dispersible hydrocolloids selected from the group consisting of sodium carboxymethylcellulose, calcium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, collagen, and gum karaya and wherein said second adhesive layer consists of from about 35% to about 50% by weight of low molecular weight polyisobutylenes and one or more optional thermoplastic elastomers selected from the group consisting of medium molecular weight polyisobutylenes, butyl rubber, and styrene-isoprene-styrene copolymers, from about 30% to about 50% by weight of one or more water dispersible hydrocolloids selected from the group consisting of sodium carboxymethylcellulose, calcium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, collagen, and gum karaya, from about 5% to about 15% by weight of mineral oil, from about 15% to about 25% by weight of a terpene resin tackifier, and less than about 5% by weight of one of more antioxidants, deodorants, and perfume agents. 
     
     
       7. The dressing of Claim 6 wherein said wound and skin contacting first adhesive layer is a homogeneous blend of about 40% by weight of low molecular weight polyisobutylene, about 20% by weight of sodium carboxymethylcellulose, about 20% by weight of pectin, and about 20% by weight of gelatin. 
     
     
       8. The dressing of Claim 7 wherein said second adhesive layer is a homogeneous blend of from about 18% by weight of low molecular weight polyisobutylenes, about 20% by weight of medium molecular weight polyisobutylenes, about 18% by weight of sodium carboxymethylcellulose, about 15% by weight of gelatin, about 20% by weight of terpene resin, about 8.5% by weight of mineral oil, and about 0.5% by weight butylated hydroxytoluene. 
     
     
       9. The dressing of Claim 8 wherein said semi open-cell polymeric foam is polyurethane foam and said water impervious polymeric film is polyurethane. 
     
     
       10. The dressing of Claim 9 wherein said wound and skin contacting first adhesive layer is from about 0.02 to about 0.1 inches in thickness, said second adhesive layer is from about 0.005 to about 0.02 inches in thickness, said polyurethane foam layer is about 0.03 to about 0.1 inches in thickness, and said water impervious polyurethane layer is about 0.001 to about 0.003 inches in thickness. 
     
     
       11. An occlusive multi-layered wound dressing consisting essentially of a first adhesive layer which in use contacts the wound and the surrounding normal skin, said first adhesive layer being of from about 0.02 to about 0.1 inches in thickness, a second adhesive layer bonded to the top surface of said first adhesive layer, said second adhesive layer being from about 0.005 to about 0.02 inches in thickness, an intermediate layer of semi-open cell polyurethane foam bonded to the upper surface of said second adhesive layer, said foam being from about 0.03 to about 0.1 inches in thickness, and an outer moisture impervious polyurethane film coated or laminated to the upper surface of said foam layer, said film being from about 0.001 to about 0.003 inches in thickness, wherein said wound and skin contacting first adhesive layer is a homogeneous blend of about 40% by weight of low molecular weight polyisobutylene, about 20% by weight of sodium carboxymethylcellulose, about 20% by weight of pectin, and about 20% by weight of gelatin, and wherein said second adhesive layer is a homogeneous blend of from about 18% by weight of low molecular weight polyisobutylenes, about 20% by weight of medium molecular weight polyisobutylenes, about 18% by weight of sodium carboxymethylcellulose, about 15% by weight of gelatin, about 20% by weight of terpene resin, about 8.5% by weight of mineral oil, and about 0.5% by weight of butylated hydroxytoluene.