US4560696AExpiredUtility

Analgesic, antipyretic or anti-inflammatory imidazole compounds

50
Assignee: ZAMBON SPAPriority: Jul 31, 1981Filed: Mar 20, 1984Granted: Dec 24, 1985
Est. expiryJul 31, 2001(expired)· nominal 20-yr term from priority
A61P 25/04A61P 29/00C07D 233/64
50
PatentIndex Score
4
Cited by
8
References
5
Claims

Abstract

New imidazole compounds of the formula ##STR1## their salts and analgesic, antipyretic and antiinflammatory pharmaceutical composition containing them. New intermediates useful in the preparation of said imidazole compounds. Process for preparing the new imidazole compounds as well as some new intermediates for the preparation thereof.

Claims

exact text as granted — not AI-modified
What we claim is: 
     
       1. 4-phenoxy-methyl-5(4-chlorophenyl)-imidazole or a pharmaceutically acceptable acid addition salt thereof. 
     
     
       2. A pharmaceutical composition for analgesic, antipyretic or anti-inflammatory use containing an effective amount of a product of the formula ##STR7## wherein R 1  is selected from the group consisting of a straight or branched chain alkyl having from 1 to 4 carbon atoms, cyclohexyl, benzyl, 5-phenyl-imidazole-4-yl-methyl, phenyl optionally substituted by chlorine, methyl, methoxy or acetamino, R 2  and R 3  are the same or different and each is selected from the group consisting of hydrogen, chlorine, methyl, methoxy, methylthio, methylsulfonyl,   R 4  is hydrogen or phenyl, or of a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier.   
     
     
       3. A pharmaceutical composition for analgesic, antipyretic or anti-inflammatory use containing an effective amount of a product of the formula ##STR8## wherein R 1  is selected from the group consisting of a straight or branched chain alkyl having from 1 to 4 carbon atoms, or of a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier.   
     
     
       4. A pharmaceutical composition for analgesic, antipyretic or anti-inflammatory use containing an effective amount of 4-ethoxy-methyl-5-(4-chlorophenyl)-imidazole or of a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier. 
     
     
       5. A pharmaceutical composition for analgesic, antipyretic or anti-inflammatory use containing an effective amount of 4-phenoxy-methyl-5-(4-chlorophenyl)-imidazole or of a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.