Crystalline antibiotic salt

Abstract

Crystalline cephalosporin hydrochloride salt represented by the formula ##STR1## wherein the oxime is in the syn configuration, is a useful pharmaceutical form of, and tool for purification of, the corresponding antibiotic free base; processes for its preparation are provided.

I claim: 
     
       1. The crystalline hydrochloride salt of the formula: ##STR4## wherein the oxime is in the syn configuration, which has the following X-ray powder diffraction pattern (Cu ++  radiation, 1.5418λ, nickel filter, d=interplanar spacing in angstrom) when crystallized from formamide-water:   ______________________________________                                    
d          Relative Intensity                                             
______________________________________                                    
13.56      25                                                             
8.61       25                                                             
7.78       75                                                             
6.88       45                                                             
5.80       15                                                             
5.13        7                                                             
4.42       100                                                            
4.29       35                                                             
4.10       55                                                             
3.98       35                                                             
3.87       40                                                             
3.64       35                                                             
3.47       60                                                             
3.16       62                                                             
3.07       18                                                             
3.00       15                                                             
2.91       15                                                             
2.80       18                                                             
2.74       22                                                             
2.60       12                                                             
2.50       20                                                             
2.45       20                                                             
2.39       15                                                             
2.23       15                                                             
2.15       15                                                             
2.12       15                                                             
2.00       20                                                             
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